Implementation of Hepatitis B Screening Into Routine Antenatal Care to Prevent Mother-to-Child Transmission in Rural Western Uganda.

Autor: Thahir S; Department of Pediatrics, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA., Muhindo E; Peoples Health and Economic Development Organization, Kasese, Uganda., Turigye B; Department of Community Health, Mbarara University of Science and Technology, Mbarara, Uganda., Kabagambe K; The National Organisation for People Living with Hepatitis B, Kampala, Uganda., Thompson P; Department of Pediatrics, Division of Infectious Diseases, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA., Mulogo EM; Department of Community Health, Mbarara University of Science and Technology, Mbarara, Uganda., Boyce RM; Department of Medicine, Division of Infectious Diseases, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.; Department of Epidemiology, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.; Carolina Population Center, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.
Jazyk: angličtina
Zdroj: Open forum infectious diseases [Open Forum Infect Dis] 2023 Aug 25; Vol. 10 (9), pp. ofad452. Date of Electronic Publication: 2023 Aug 25 (Print Publication: 2023).
DOI: 10.1093/ofid/ofad452
Abstrakt: In rural Uganda where birth dose vaccination for hepatitis B is not routine, we implemented a pilot program for preventing mother-to-child transmission that effectively identified women with high-risk hepatitis B virus (HBV) infection and started antiviral treatment during pregnancy. Further work is required to enhance antiviral adherence through delivery to ensure effective prevention of vertical HBV transmission.
Competing Interests: Potential conflicts of interest. P. T. received funding from the National Institutes of Health (grant K08AI148607), the American Society of Tropical Medicine and Hygiene/Burroughs-Wellcome Fund, and Novavax, outside of the current work, as well as research support from Abbott Laboratories and Gilead Sciences, also outside of the current work.
(© The Author(s) 2023. Published by Oxford University Press on behalf of Infectious Diseases Society of America.)
Databáze: MEDLINE
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