High-Frame-Rate Volumetric Porcine Renal Vasculature Imaging.

Autor:	Wei L; Department of Cardiology, Erasmus MC University Medical Center, Rotterdam, The Netherlands. Electronic address: l.wei@erasmusmc.nl., Wahyulaksana G; Department of Cardiology, Erasmus MC University Medical Center, Rotterdam, The Netherlands., Te Lintel Hekkert M; Department of Cardiology, Erasmus MC University Medical Center, Rotterdam, The Netherlands., Beurskens R; Department of Cardiology, Erasmus MC University Medical Center, Rotterdam, The Netherlands., Boni E; Department of Information Engineering, University of Florence, Florence, Italy., Ramalli A; Department of Information Engineering, University of Florence, Florence, Italy., Noothout E; Department of Imaging Physics, Delft University of Technology, Delft, The Netherlands., Duncker DJ; Department of Cardiology, Erasmus MC University Medical Center, Rotterdam, The Netherlands., Tortoli P; Department of Information Engineering, University of Florence, Florence, Italy., van der Steen AFW; Department of Cardiology, Erasmus MC University Medical Center, Rotterdam, The Netherlands; Department of Imaging Physics, Delft University of Technology, Delft, The Netherlands., de Jong N; Department of Cardiology, Erasmus MC University Medical Center, Rotterdam, The Netherlands; Department of Imaging Physics, Delft University of Technology, Delft, The Netherlands., Verweij M; Department of Cardiology, Erasmus MC University Medical Center, Rotterdam, The Netherlands; Department of Imaging Physics, Delft University of Technology, Delft, The Netherlands., Vos HJ; Department of Cardiology, Erasmus MC University Medical Center, Rotterdam, The Netherlands; Department of Imaging Physics, Delft University of Technology, Delft, The Netherlands.
Jazyk:	angličtina
Zdroj:	Ultrasound in medicine & biology [Ultrasound Med Biol] 2023 Dec; Vol. 49 (12), pp. 2476-2482. Date of Electronic Publication: 2023 Sep 11.
DOI:	10.1016/j.ultrasmedbio.2023.08.009
Abstrakt:	Objective: The aim of this study was to assess the feasibility and imaging options of contrast-enhanced volumetric ultrasound kidney vasculature imaging in a porcine model using a prototype sparse spiral array. Methods: Transcutaneous freehand in vivo imaging of two healthy porcine kidneys was performed according to three protocols with different microbubble concentrations and transmission sequences. Combining high-frame-rate transmission sequences with our previously described spatial coherence beamformer, we determined the ability to produce detailed volumetric images of the vasculature. We also determined power, color and spectral Doppler, as well as super-resolved microvasculature in a volume. The results were compared against a clinical 2-D ultrasound machine. Results: Three-dimensional visualization of the kidney vasculature structure and blood flow was possible with our method. Good structural agreement was found between the visualized vasculature structure and the 2-D reference. Microvasculature patterns in the kidney cortex were visible with super-resolution processing. Blood flow velocity estimations were within a physiological range and pattern, also in agreement with the 2-D reference results. Conclusion: Volumetric imaging of the kidney vasculature was possible using a prototype sparse spiral array. Reliable structural and temporal information could be extracted from these imaging results. Competing Interests: Conflict of interest The authors declare no competing interests. (Copyright © 2023 The Authors. Published by Elsevier Inc. All rights reserved.)
Databáze:	MEDLINE
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