Why and How to Account for Sex and Gender in Brain and Behavioral Research.
| Autor: | Eliot L; Stanson Toshok Center for Brain Function and Repair, Chicago Medical School, Rosalind Franklin University of Medicine & Science, North Chicago, Illinois 60064 lise.eliot@rosalindfranklin.edu., Beery AK; Department of Integrative Biology, University of California-Berkeley, Berkeley, California 94720., Jacobs EG; Department of Psychological & Brain Sciences, University of California-Santa Barbara, Santa Barbara, California 93106., LeBlanc HF; Division of the Humanities & Social Sciences, California Institute of Technology, Pasadena, California 91125., Maney DL; Department of Psychology, Emory University, Atlanta, Georgia 30322., McCarthy MM; Department of Pharmacology, University of Maryland School of Medicine, Baltimore, Maryland 21201. |
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| Jazyk: | angličtina |
| Zdroj: | The Journal of neuroscience : the official journal of the Society for Neuroscience [J Neurosci] 2023 Sep 13; Vol. 43 (37), pp. 6344-6356. |
| DOI: | 10.1523/JNEUROSCI.0020-23.2023 |
| Abstrakt: | Long overlooked in neuroscience research, sex and gender are increasingly included as key variables potentially impacting all levels of neurobehavioral analysis. Still, many neuroscientists do not understand the difference between the terms "sex" and "gender," the complexity and nuance of each, or how to best include them as variables in research designs. This TechSights article outlines rationales for considering the influence of sex and gender across taxa, and provides technical guidance for strengthening the rigor and reproducibility of such analyses. This guidance includes the use of appropriate statistical methods for comparing groups as well as controls for key covariates of sex (e.g., total intracranial volume) and gender (e.g., income, caregiver stress, bias). We also recommend approaches for interpreting and communicating sex- and gender-related findings about the brain, which have often been misconstrued by neuroscientists and the lay public alike. (Copyright © 2023 the authors.) |
| Databáze: | MEDLINE |
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