Pharmacokinetics of albendazole in man.

Autor: Marriner SE, Morris DL, Dickson B, Bogan JA
Jazyk: angličtina
Zdroj: European journal of clinical pharmacology [Eur J Clin Pharmacol] 1986; Vol. 30 (6), pp. 705-8.
DOI: 10.1007/BF00608219
Abstrakt: The pharmacokinetics of albendazole were investigated in healthy volunteers and in patients receiving albendazole for treatment of hydatid disease. Unchanged albendazole was below detectable limits in plasma, urine, bile and cyst fluid. The major metabolite present in all fluids was the sulfoxide. Maximum concentrations of albendazole sulfoxide in plasma were very variable, probably due to variable absorption of albendazole.
Databáze: MEDLINE