Development, stabilization, and characterization of nanoemulsion of vitamin D 3 -enriched canola oil.

Autor: Khalid A; Department of Food Science, Government College University, Faisalabad, Pakistan., Arshad MU; Department of Food Science, Government College University, Faisalabad, Pakistan., Imran A; Department of Food Science, Government College University, Faisalabad, Pakistan., Haroon Khalid S; Department of Pharmaceutics, Government College University, Faisalabad, Pakistan., Shah MA; School of Business, Woxsen University, Hyderabad, Telangana, India.; Division of Research and Development, Lovely Professional University, Phagwara, Punjab, India.; School of Engineering and Technology, Sharda University, Greater Noida, India.; Department of Economics, Kabridahar University, Somali, Ethiopia.
Jazyk: angličtina
Zdroj: Frontiers in nutrition [Front Nutr] 2023 Aug 24; Vol. 10, pp. 1205200. Date of Electronic Publication: 2023 Aug 24 (Print Publication: 2023).
DOI: 10.3389/fnut.2023.1205200
Abstrakt: In this study, the oil-in-water nanoemulsion (NE) was prepared and loaded with vitamin D 3 in food-grade (edible) canola oil and stabilized by Tween 80 and Span 80 by using a water titration technique with droplet sizes of 20 to 200 nm. A phase diagram was established for the influence of water, oil, and S-Mix concentration. The outcomes revealed that the particle size of blank canola oil nanoemulsion (NE) ranged from 60.12 to 62.27 (d.nm) and vitamin D 3 NE ranged from 93.92 to 185.5 (d.nm). Droplet size and polydispersity index (PDI) of both blank and vitamin D 3 -loaded NE results were less than 1, and zeta potential results for blank and vitamin D 3 loaded NE ranged from -9.71 to -15.32 mV and -7.29 to -13.56 mV, respectively. Furthermore, the pH and electrical conductivity of blank NE were 6.0 to 6.2 and 20 to 100 (μs/cm), respectively, whereas vitamin D 3 -loaded NE results were 6.0 to 6.2 and 30 to 100 (μs/cm), respectively. The viscosity results of blank NE ranged from 0.544 to 0.789 (mPa.s), while that of vitamin D 3 -loaded NE ranged from 0.613 to 0.793 (mPa.s). In this study, the long-term stability (3 months) of canola oil NE containing vitamin D3 at room temperature (25 C) and high temperature (40 C) was observed.
Competing Interests: The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.
(Copyright © 2023 Khalid, Arshad, Imran, Haroon Khalid and Shah.)
Databáze: MEDLINE
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