Comparison of Long-Term Outcomes of Patients With Myocardia Infarction (MI) With Non-obstructive Coronary Arteries and MI With Obstructive Coronary Arteries: A Systematic Review and Meta-Analysis.

Autor:	Naeem MO; Pathology, Rehman Medical Institute, Peshawar, PAK., Khan SK; Medicine, Army Medical College, Rawalpindi, PAK., Gergess RR; Internal Medicine, Universidad Autónoma de Guadalajara, Guadalajara, MEX., Addi Palle LR; Surgery, Kamala Hospital, Chennai, IND.; General Surgery, Hackensack Meridian Health Palisades Medical Center, North Bergen, USA., Krupanagaram S; Medicine, MNR Medical College and Hospital, Sangareddy, IND., Khan MW; Medicine, Services Institute of Medical Sciences, Lahore, PAK., Haseeb MD; Neurology, Dow University of Health Sciences, Karachi, PAK., Hirani S; Cardiology, Baqai Hospital, Karachi, PAK.
Jazyk:	angličtina
Zdroj:	Cureus [Cureus] 2023 Aug 08; Vol. 15 (8), pp. e43137. Date of Electronic Publication: 2023 Aug 08 (Print Publication: 2023).
DOI:	10.7759/cureus.43137
Abstrakt:	The aim of this study was to compare long-term outcomes in patients with myocardial infarction with non-obstructive coronary arteries (MINOCA) and patients with myocardial infarction with obstructive coronary arteries (MIOCA). This meta-analysis was conducted according to the recommendations of the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA). The literature search was conducted in online databases including PubMed and Web of Science from 2010 onwards. Primary outcomes assessed in this meta-analysis included major adverse cardiovascular events (MACE) and all-cause mortality. Secondary outcomes included cardiovascular mortality and myocardial infarction. A total of 16 studies were included in the meta-analysis. Pooled analysis showed that the risk of MACE was higher in MIOCA patients (risk ratio (RR): 1.47, 95%CI: 1.43-1.52, p-value: 0.001) compared to MINOCA patients. Additionally, the risk of all-cause mortality was also significantly higher in MIOCA patients compared to MINOCA (RR: 1.33, 95%CI: 1.14-1.56, p-value: 0.001). Our findings also indicate that patients with MIOCA are at a significantly higher risk of recurrent myocardial infarction and cardiovascular-related mortality compared to patients with MINOCA. Overall, the insights gained from this meta-analysis have significant clinical implications, guiding decision-making in the management of patients with MINOCA. Competing Interests: The authors have declared that no competing interests exist. (Copyright © 2023, Naeem et al.)
Databáze:	MEDLINE
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