Recent Trends in the Management of Eosinophilic Esophagitis: A Systematic Review.

Autor:	Dutta P; Internal Medicine, Trinity Health Ann Arbor, Ypsilanti, USA., Shah-Riar P; Internal Medicine, Ibn Sina Medical College, Dhaka, BGD.; Internal Medicine, University Muslim Medical Association Community Clinic, Los Angeles, USA., Bushra SS; Internal Medicine, Jahurul Islam Medical College & Hospital, Kishoreganj, BGD., Haque SN; Internal Medicine, Dhaka Medical College Hospital, Dhaka, BGD., Rafa ZI; Internal Medicine, Ibn Sina Medical College and Hospital, Dhaka, BGD., Hawa F; Internal Medicine, St. Joseph Mercy Ann Arbor Hospital, Ann Arbor, USA.; Internal Medicine/Gastroenterology and Hepatology, University of Michigan, Ann Arbor, USA., Chakrabarty S; Internal Medicine, North East Medical College, Sylhet, BGD., Dev Nath S; Pulmonary and Critical Care Medicine, Johns Hopkins University, Baltimore, USA., Afrin H; Radiology, Mayo Clinic, Rochester, USA., Shama N; Internal Medicine, Bangladesh Institute of Research and Rehabilitation in Diabetes, Endocrine and Metabolic Disorders, Dhaka, BGD., Khair F; Internal Medicine, Bangladesh Medical College & Hospital, Dhaka, BGD., Maisha S; Internal Medicine, Sher-e-Bangla Medical College, Barisal, BGD., Kapuria P; Internal Medicine, Z.H. Sikder Women's Medical College and Hospital, Dhaka, BGD., Dam B; Internal Medicine, Kumudini Women's Medical College, Tangail, BGD.
Jazyk:	angličtina
Zdroj:	Cureus [Cureus] 2023 Aug 09; Vol. 15 (8), pp. e43221. Date of Electronic Publication: 2023 Aug 09 (Print Publication: 2023).
DOI:	10.7759/cureus.43221
Abstrakt:	Eosinophilic esophagitis (EoE) is a chronic immune-mediated condition characterized by inflammation and eosinophilic accumulation of the esophagus, resulting in dysphagia and food impaction. While the exact etiology of EoE remains unclear, it is believed to be triggered by food allergens and dynamic environmental factors, resulting in various clinical manifestations, from inflammation to fibrosis. Although clinical presentation varies with age, the number of eosinophils in esophagogastroduodenal endoscopy remains the diagnostic gold standard. While diet elimination, proton pump inhibitors (PPIs), topical corticosteroids, and biological therapy are promising treatment options for EoE, there are insufficient data to determine the optimal therapeutic treatment approach. Combination therapies - the use of dietary therapies in conjunction with other treatment modalities, such as PPIs, topical corticosteroids, or biologic agents - have also emerged as a potential management strategy for EoE. In this systematic review, we attempt to highlight the recent advances in EoE therapies and provide updated guidance to their management. From 2017 to 2022, we conducted a comprehensive electronic search of PubMed (MEDLINE) using specific keywords related to our objective and eventually included a total of 44 articles. Competing Interests: The authors have declared that no competing interests exist. (Copyright © 2023, Dutta et al.)
Databáze:	MEDLINE
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