The potential modulation of gut microbiota and oxidative stress by dietary carotenoid pigments.

Autor:	Bernabeu M; Research Group in Innovative Technologies for Sustainable Food (ALISOST), Preventive Medicine and Public Health, Food Science, Toxicology and Forensic Medicine Department, Faculty of Pharmacy, Universitat de València, Avda, Burjassot, Burjassot, València, Spain.; Vicerectorat de Recerca, Universitat de Barcelona (UB), Barcelona, Spain., Gharibzahedi SMT; Faculty of Natural Sciences and Maths, Institute of Chemistry, Technical University of Berlin, Berlin, Germany.; Faculty of Engineering, Institute of Materials Science, Kiel University, Kiel, Germany., Ganaie AA; Watson Crick Centre for Molecular Medicine, Islamic University of Science and Technology, Kashmir, India., Macha MA; Watson Crick Centre for Molecular Medicine, Islamic University of Science and Technology, Kashmir, India., Dar BN; Department of Food Technology, Islamic University of Science and Technology, Kashmir, India., Castagnini JM; Research Group in Innovative Technologies for Sustainable Food (ALISOST), Preventive Medicine and Public Health, Food Science, Toxicology and Forensic Medicine Department, Faculty of Pharmacy, Universitat de València, Avda, Burjassot, Burjassot, València, Spain., Garcia-Bonillo C; Facultad de Ciencias de la Salud, European University of Valencia, Valencia, Spain., Meléndez-Martínez AJ; Facultad de Farmacia, Food Colour and Quality Laboratory, Universidad de Sevilla, Sevilla, Spain., Altintas Z; Faculty of Natural Sciences and Maths, Institute of Chemistry, Technical University of Berlin, Berlin, Germany.; Faculty of Engineering, Institute of Materials Science, Kiel University, Kiel, Germany., Barba FJ; Research Group in Innovative Technologies for Sustainable Food (ALISOST), Preventive Medicine and Public Health, Food Science, Toxicology and Forensic Medicine Department, Faculty of Pharmacy, Universitat de València, Avda, Burjassot, Burjassot, València, Spain.
Jazyk:	angličtina
Zdroj:	Critical reviews in food science and nutrition [Crit Rev Food Sci Nutr] 2023 Sep 10, pp. 1-19. Date of Electronic Publication: 2023 Sep 10.
DOI:	10.1080/10408398.2023.2254383
Abstrakt:	Gut microbiota plays a crucial role in regulating the response to immune checkpoint therapy, therefore modulation of the microbiome with bioactive molecules like carotenoids might be a very effective strategy to reduce the risk of chronic diseases. This review highlights the bio-functional effect of carotenoids on Gut Microbiota modulation based on a bibliographic search of the different databases. The methodology given in the preferred reporting items for systematic reviews and meta-analyses (PRISMA) has been employed for developing this review using papers published over two decades considering keywords related to carotenoids and gut microbiota. Moreover, studies related to the health-promoting properties of carotenoids and their utilization in the modulation of gut microbiota have been presented. Results showed that there can be quantitative changes in intestinal bacteria as a function of the type of carotenoid. Due to the dependency on several factors, gut microbiota continues to be a broad and complex study subject. Carotenoids are promising in the modulation of Gut Microbiota, which favored the appearance of beneficial bacteria, resulting in the protection of villi and intestinal permeability. In conclusion, it can be stated that carotenoids may help to protect the integrity of the intestinal epithelium from pathogens and activate immune cells.
Databáze:	MEDLINE
Externí odkaz:	Zobrazit plný text záznamu