Embedding implementation science in the research pipeline.

Autor:	Zullig LL; Center of Innovation to Accelerate Discovery and Practice Transformation, Durham Veterans Affairs Health Care System, Durham, NC, USA.; Department of Population Health Sciences, Duke University School of Medicine, Durham, NC, USA., Drake C; Center of Innovation to Accelerate Discovery and Practice Transformation, Durham Veterans Affairs Health Care System, Durham, NC, USA.; Department of Population Health Sciences, Duke University School of Medicine, Durham, NC, USA., Check DK; Department of Population Health Sciences, Duke University School of Medicine, Durham, NC, USA., Brunkert T; Institute of Nursing Science, Department Public Health, University of Basel, Basel, Switzerland.; University Department of Geriatric Medicine, Basel, Switzerland., Deschodt M; Gerontology and Geriatrics, Department of Public Health and Primary Care, KU Leuven, Leuven, Belgium.; Competence Center of Nursing, University Hospitals Leuven, Leuven, Belgium., Olson MS; Evidence Generation, Medical Affairs, Novartis Pharma AG, Basel, Switzerland., De Geest S; Institute of Nursing Science, Department Public Health, University of Basel, Basel, Switzerland.; Academic Centre for Nursing and Midwifery, Department of Public Health and Primary Care, KU Leuven, Leuven, Belgium.
Jazyk:	angličtina
Zdroj:	Translational behavioral medicine [Transl Behav Med] 2024 Feb 07; Vol. 14 (2), pp. 73-79.
DOI:	10.1093/tbm/ibad050
Abstrakt:	Clinical and health services researchers seek to discover effective programs, practices, and interventions to improve people's health. The current paradigm for evidence generation is incremental and misaligned to translate evidence-based discoveries into real-world settings. This persistent challenge are "valleys of death" that represent missed opportunities and preventable missteps to actually use scientific advancements in real-world clinical settings where they can improve health and well-being (De Geest S, Zúñiga F, Brunkert T et al. Powering Swiss health care for the future: implementation science to bridge "the valley of death". 2020;150:w20323). Only one in seven of evidence-based interventions is ever implemented. It is after an average of 17 years. We propose embedding the principles of implementation science throughout the research pipeline, from discovery to adoption, to efficiently translate discoveries into real-world contexts (Balas EA, Boren SA. Managing clinical knowledge for health care improvement. 2000;9:65-70). We outline implications for capacity building, including composition of the research team, study design, and competencies that could bolster the value proposition of implementation science. We describe a research paradigm that recognizes scientists' responsibility to ensure their discoveries be translated into real-world settings. (Published by Oxford University Press on behalf of the Society of Behavioral Medicine 2023.)
Databáze:	MEDLINE
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