Maintenance Therapy for Children and Adolescents with Asthma: Guidelines and Recommendations from the Emilia-Romagna Asthma (ERA) Study Group.

Autor: Fainardi V; Pediatric Clinic, Department of Medicine and Surgery, University of Parma, 43126 Parma, Italy., Caffarelli C; Pediatric Clinic, Department of Medicine and Surgery, University of Parma, 43126 Parma, Italy., Deolmi M; Pediatric Clinic, Department of Medicine and Surgery, University of Parma, 43126 Parma, Italy., Zambelli G; Pediatric Clinic, Department of Medicine and Surgery, University of Parma, 43126 Parma, Italy., Palazzolo E; Pediatric Clinic, Department of Medicine and Surgery, University of Parma, 43126 Parma, Italy., Scavone S; Pediatric Clinic, Department of Medicine and Surgery, University of Parma, 43126 Parma, Italy., Bergamini BM; Paediatric Unit, Department of Medical and Surgical Sciences of Mothers, Children and Adults, University of Modena and Reggio Emilia, 41125 Modena, Italy., Bertelli L; Pediatric Clinic, Scientific Institute for Research and Healthcare (IRCCS) Azienda Ospedaliero-Universitaria di Bologna, 40138 Bologna, Italy., Biserna L; Paediatrics and Neonatology Unit, Ravenna Hospital, Azienda Unità Sanitaria Locale (AUSL) Romagna, 48121 Ravenna, Italy., Bottau P; Paediatrics Unit, Imola Hospital, 40026 Imola, Italy., Corinaldesi E; Paediatric Unit, Carpi Hospital, 41012 Carpi, Italy., De Paulis N; Paediatrics and Neonatology Unit, Guglielmo da Saliceto Hospital, 29121 Piacenza, Italy., Di Palmo E; Pediatric Clinic, Scientific Institute for Research and Healthcare (IRCCS) Azienda Ospedaliero-Universitaria di Bologna, 40138 Bologna, Italy., Dondi A; Pediatric Clinic, Scientific Institute for Research and Healthcare (IRCCS) Azienda Ospedaliero-Universitaria di Bologna, 40138 Bologna, Italy., Gallucci M; Pediatric Clinic, Scientific Institute for Research and Healthcare (IRCCS) Azienda Ospedaliero-Universitaria di Bologna, 40138 Bologna, Italy., Guidi B; Hospital and Territorial Paediatrics Unit, 41026 Pavullo, Italy., Lombardi F; Paediatrics Unit, Maggiore Hospital, 40133 Bologna, Italy., Magistrali MS; Paediatrics and Neonatology Unit, Guglielmo da Saliceto Hospital, 29121 Piacenza, Italy., Marastoni E; Paediatrics Unit, Santa Maria Nuova Hospital, Azienda Unità Sanitaria Locale (AUSL)-Scientific Institute for Research and Healthcare (IRCCS) of Reggio Emilia, 42123 Reggio Emilia, Italy., Pastorelli S; Paediatrics Unit, Sassuolo Hospital, 41049 Sassuolo, Italy., Piccorossi A; Paediatrics and Paediatric Intensive Care Unit, Cesena Hospital, Azienda Unità Sanitaria Locale (AUSL) Romagna, 47521 Cesena, Italy., Poloni M; Paediatrics Unit, Rimini Hospital, Azienda Unità Sanitaria Locale (AUSL) Romagna, 47921 Rimini, Italy., Tagliati S; Paediatric Clinic, Ferrara Hospital, 44124 Ferrara, Italy., Vaienti F; Paediatrics Unit, G.B. Morgagni Pierantoni Hospital, Azienda Unità Sanitaria Locale (AUSL) Romagna, 47121 Forlì, Italy., Gregori G; Primary Care Pediatricians, Azienda Unità Sanitaria Locale (AUSL) Piacenza, 29121 Piacenza, Italy., Sacchetti R; Primary Care Pediatricians, Azienda Unità Sanitaria Locale (AUSL) Piacenza, 29121 Piacenza, Italy., Antodaro F; Primary Care Pediatricians, Azienda Unità Sanitaria Locale (AUSL) Modena, 41125 Modena, Italy., Bergomi A; Primary Care Pediatricians, Azienda Unità Sanitaria Locale (AUSL) Modena, 41125 Modena, Italy., Reggiani L; Primary Care Pediatricians, Azienda Unità Sanitaria Locale (AUSL) Imola, 40026 Imola, Italy., De Fanti A; Paediatrics Unit, Santa Maria Nuova Hospital, Azienda Unità Sanitaria Locale (AUSL)-Scientific Institute for Research and Healthcare (IRCCS) of Reggio Emilia, 42123 Reggio Emilia, Italy., Marchetti F; Paediatrics and Neonatology Unit, Ravenna Hospital, Azienda Unità Sanitaria Locale (AUSL) Romagna, 48121 Ravenna, Italy., Grandinetti R; Pediatric Clinic, Department of Medicine and Surgery, University of Parma, 43126 Parma, Italy., Mussi N; Pediatric Clinic, Department of Medicine and Surgery, University of Parma, 43126 Parma, Italy., Ricci G; Pediatric Clinic, Scientific Institute for Research and Healthcare (IRCCS) Azienda Ospedaliero-Universitaria di Bologna, 40138 Bologna, Italy., Esposito S; Pediatric Clinic, Department of Medicine and Surgery, University of Parma, 43126 Parma, Italy.
Jazyk: angličtina
Zdroj: Journal of clinical medicine [J Clin Med] 2023 Aug 23; Vol. 12 (17). Date of Electronic Publication: 2023 Aug 23.
DOI: 10.3390/jcm12175467
Abstrakt: Asthma is the most frequent chronic disease of childhood, affecting up to 20% of children worldwide. The main guidelines on asthma maintenance therapy in pediatrics suggest different approaches and describe different stages of asthma to determine the most appropriate treatment. This project aims to summarize the most recent evidence regarding maintenance therapy for asthma in children and adolescents. A multidisciplinary panel of experts was asked clinical questions regarding the treatment of children and adolescents with asthma. Overall, 10 clinical questions were addressed, and the search strategy included accessing electronic databases and a manual search of gray literature published in the last 25 years. After data extraction and narrative synthesis of results, recommendations were developed using the Grading of Recommendations, Assessment, Development, and Evaluations (GRADE) methodology. Results showed that the choice of medication depends on the severity of the child's asthma, phenotype, age, preference, and individual factors. In addition to medications, the identification of comorbidities and modifiable factors is crucial to obtaining good control. Asthma in children is heterogeneous, and its evolution varies over time. Since most recommendations for asthma management in childhood are extrapolated from clinical studies performed in adults, more clinical trials specifically designed for young children should be conducted.
Databáze: MEDLINE
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