Native Renal Arteries Denervation as a Therapy of Refractory Hypertension in Patient after Heart and Kidney Transplantation-5 Years of Observation.

Autor: Pilch J; Faculty of Medicine, Wroclaw Medical University, 50-368 Wroclaw, Poland., Mizera J; Faculty of Medicine, Wroclaw Medical University, 50-368 Wroclaw, Poland., Wiśnicki K; Clinical Department of Nephrology and Transplantation Medicine, Wroclaw Medical University, 50-556 Wroclaw, Poland., Protasiewicz M; Clinical Department of Cardiology, Wroclaw Medical University, 50-556 Wroclaw, Poland.; Institute of Heart Diseases, University Hospital, 50-556 Wroclaw, Poland., Kurcz J; Clinical Department of Radiology, Wroclaw Medical University, 50-556 Wroclaw, Poland., Zmonarski S; Clinical Department of Nephrology and Transplantation Medicine, Wroclaw Medical University, 50-556 Wroclaw, Poland., Wawrzonkowski P; Clinical Department of Nephrology and Transplantation Medicine, Wroclaw Medical University, 50-556 Wroclaw, Poland., Letachowicz K; Clinical Department of Nephrology and Transplantation Medicine, Wroclaw Medical University, 50-556 Wroclaw, Poland., Kamińska D; Clinical Department of Nephrology and Transplantation Medicine, Wroclaw Medical University, 50-556 Wroclaw, Poland., Gołębiowski T; Clinical Department of Nephrology and Transplantation Medicine, Wroclaw Medical University, 50-556 Wroclaw, Poland., Zakliczyński M; Institute of Heart Diseases, University Hospital, 50-556 Wroclaw, Poland.; Clinic of Cardiac Transplantation and Mechanical Circulatory Support, Wroclaw Medical University, 50-556 Wroclaw, Poland., Krajewska M; Clinical Department of Nephrology and Transplantation Medicine, Wroclaw Medical University, 50-556 Wroclaw, Poland., Banasik M; Clinical Department of Nephrology and Transplantation Medicine, Wroclaw Medical University, 50-556 Wroclaw, Poland.
Jazyk: angličtina
Zdroj: Journal of clinical medicine [J Clin Med] 2023 Aug 23; Vol. 12 (17). Date of Electronic Publication: 2023 Aug 23.
DOI: 10.3390/jcm12175458
Abstrakt: This case report describes a 59-year-old male patient after heart and kidney transplantation, subsequently diagnosed with refractory hypertension since implemented antihypertensive pharmacotherapy consisting of six agents did not provide a substantial therapeutic response. Elevated blood pressure and its impact on a hypertrophied transplanted heart and impaired renal graft function have led to a significant deterioration in the patient's cardiovascular risk profile. To address this issue, a native renal arteries denervation was performed. It resulted in a noteworthy decrease in both systolic and diastolic pressure values, thus manifesting a positive hypotensive effect. Furthermore, a sustainable reduction of left ventricular mass and stabilization in kidney graft function were noticed. The presented case provides evidence that renal denervation can be an efficacious complementary treatment method in individuals who received kidney and heart grafts as it leads to a decrease in cardiovascular risk.
Databáze: MEDLINE
Externí odkaz:
Nepřihlášeným uživatelům se plný text nezobrazuje