Patterns of Electrocardiographic Abnormalities in Children with Hypertrophic Cardiomyopathy.

Autor: Marshall M; Cleveland Clinic Children's Hospital, Cleveland, OH, USA., Malik A; University of Los Angeles Olive View, Los Angeles, CA, USA., Shah M; Children's Hospital of Philadelphia, Philadelphia, PA, USA., Fish FA; Vanderbilt University, Nashville, TN, USA., Etheridge SP; University of Utah, Salt Lake City, UT, USA., Aziz PF; Cleveland Clinic Children's Hospital, Cleveland, OH, USA., Russell MW; C.S. Mott Children's Hospital, Ann Arbor, MI, USA., Tisma S; Nemours Children's Hospital, Wilmington, DE, USA., Pflaumer A; Royal Children's Hospital, University of Melbourne, Parkville, VIC, Australia., Sreeram N; University of Cologne, Cologne, Germany., Kubus P; Motol University, Prague, Czech Republic., Law IH; University of Iowa, Iowa City, IA, USA., Kantoch MJ; University of Alberta, Edmonton, AB, Canada., Kertesz NJ; Nationwide Children's Hospital, Columbus, OH, USA., Strieper M; Children's Healthcare of Atlanta, Emory University, Atlanta, GA, USA., Erickson CC; Children's Specialty Physicians, University of Nebraska Medical Center, Omaha, NE, USA., Moore JP; University of California, Los Angeles, CA, USA., Nakano SJ; University of Colorado, Denver, CO, USA., Singh HR; Children's Hospital of San Antonio, Baylor College of Medicine, San Antonio, TX, USA., Chang P; Children's Mercy Hospital, Kansas City, MO, USA., Cohen M; Inova LJ Murphy Children's Hospital, Falls Church, VA, USA., Fournier A; University of Montreal, Montreal, QC, Canada., Ilina MV; Royal Children's Hospital, Glasgow, Scotland, UK., Zimmermann F; Advocate Hospital, Chicago, IL, USA., Horndasch M; German Heart Center, Munich, Germany., Li W; University of California, San Francisco, CA, USA., Batra AS; University of California, Irvine, CA, USA., Liberman L; Columbia University, New York, NY, USA., Hamilton R; Hospital for Sick Kids, Toronto, ON, Canada., Janson CM; Children's Hospital of Philadelphia, Philadelphia, PA, USA., Sanatani S; University of British Columbia, Vancouver, BC, Canada., Zeltser I; University of Texas-Southwestern, Dallas, TX, USA., McDaniel G; University of Virginia, Charlottesville, VA, USA., Blaufox AD; Zucker School of Medicine at Hofstra/Northwell, Hempstead, NY, USA., Garnreiter JM; Saint Louis University, Saint Louis, MO, USA., Balaji S; Oregon Health and Science University, 707 SW Gaines Street, Portland, OR, 97239, USA. balajis@ohsu.edu.
Jazyk: angličtina
Zdroj: Pediatric cardiology [Pediatr Cardiol] 2024 Dec; Vol. 45 (8), pp. 1692-1701. Date of Electronic Publication: 2023 Sep 09.
DOI: 10.1007/s00246-023-03252-4
Abstrakt: Hypertrophic cardiomyopathy (HCM), a common cardiomyopathy in children, is an important cause of morbidity and mortality. Early recognition and appropriate management are important. An electrocardiogram (ECG) is often used as a screening tool in children to detect heart disease. The ECG patterns in children with HCM are not well described.ECGs collected from an international cohort of children, and adolescents (≤ 21 years) with HCM were reviewed. 482 ECGs met inclusion criteria. Age ranged from 1 day to 21 years, median 13 years. Of the 482 ECGs, 57 (12%) were normal. The most common abnormalities noted were left ventricular hypertrophy (LVH) in 108/482 (22%) and biventricular hypertrophy (BVH) in 116/482 (24%) Of the patients with LVH/BVH (n = 224), 135 (60%) also had a strain pattern (LVH in 83, BVH in 52). Isolated strain pattern (in the absence of criteria for hypertrophy) was seen in 43/482 (9%). Isolated pathologic Q waves were seen in 71/482 (15%). Pediatric HCM, 88% have an abnormal ECG. The most common ECG abnormalities were LVH or BVH with or without strain. Strain pattern without hypertrophy and a pathologic Q wave were present in a significant proportion (24%) of patients. Thus, a significant number of children with HCM have ECG abnormalities that are not typical for "hypertrophy". The presence of the ECG abnormalities described above in a child should prompt further examination with an echocardiogram to rule out HCM.
(© 2023. The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature.)
Databáze: MEDLINE
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