| Autor: |
Few JD, Paintin DB, James VH |
| Jazyk: |
angličtina |
| Zdroj: |
British journal of obstetrics and gynaecology [Br J Obstet Gynaecol] 1986 Sep; Vol. 93 (9), pp. 928-32. |
| DOI: |
10.1111/j.1471-0528.1986.tb08010.x |
| Abstrakt: |
The concentrations of aldosterone and glucocorticoids (cortisol + cortisone) were measured in saliva and plasma samples obtained from healthy women during early (11-19 weeks), mid (24-29 weeks) and late (32-37 weeks) pregnancy. There was a progressive increase in mean aldosterone levels in both saliva and plasma throughout pregnancy, though at each stage of pregnancy the range was very wide. Glucocorticoid levels increased up to mid-pregnancy and then remained constant. At no stage were aldosterone and glucocorticoid levels significantly correlated. The proportion of free (non-protein bound) aldosterone in plasma, and the saliva:plasma ratio of aldosterone did not differ from the non-pregnant range at any stage of pregnancy. We conclude that measurement of aldosterone concentration in saliva is a convenient and valid method for the estimation of plasma free aldosterone in pregnancy and so provide a non-invasive technique for assessing aldosterone status throughout pregnancy. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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