[ICG angiography in prevention of colorectal anastomotic leakage].

Autor:	Bedzhanyan AL; Petrovsky National Research Center of Surgery, Moscow, Russia., Petrenko KN; Petrovsky National Research Center of Surgery, Moscow, Russia., Sumbaev AA; Petrovsky National Research Center of Surgery, Moscow, Russia., Frolova YV; Petrovsky National Research Center of Surgery, Moscow, Russia., Nikoda VV; Petrovsky National Research Center of Surgery, Moscow, Russia., Butenko AV; Petrovsky National Research Center of Surgery, Moscow, Russia.
Jazyk:	ruština
Zdroj:	Khirurgiia [Khirurgiia (Mosk)] 2023 (9. Vyp. 2), pp. 25-32.
DOI:	10.17116/hirurgia202309225
Abstrakt:	Objective: To evaluate the effectiveness of indocyanine green fluorescence angiography in assessment of colorectal anastomosis perfusion. Material and Methods: A prospective single-center non-randomized comparative study included 85 patients with rectum and sigmoid colon cancer between September 2019 and March 2023. In the main group ( n =41), we intraoperatively injected indocyanine green (ICG) IV to assess perfusion in the near infrared spectrum. In the control group ( n =44), the same interventions were performed without ICG. Results: In the main group, anterior resection of the rectum was performed in 23 (56.1%) patients with neoplasms of distal sigmoid colon and rectosigmoid tumors. Low anterior resection was performed in 18 (43.9%) cases. In the control group, the same procedures were carried out in 24 (54.5%) and 20 (45.5%) patients, respectively. After mobilization of the colon and ICG injection, we corrected resection line in 4 cases. As soon as anastomosis was formed and blood supply was controlled by ICG fluorescence angiography, we performed a water-bubble test to detect anastomotic leakage. Positive tests were detected in 4 (9.8%) and 5 (11.4%) patients of both groups, respectively. Postoperative complications occurred in 10 (24.4%) and 11 (27.3%) patients, respectively ( p =0.94). Anastomosis failure was found in 1 and 7 patients, respectively. Anastomotic leakage grade «B» was significantly more common in the control group (2.4 and 13.6%, respectively, p =0.06). Anastomotic leaks were absent in all 4 patients who underwent resection level adjustment after intraoperative ICG angiography. Conclusion: Fluorescent luminescence will qualitatively improve intraoperative diagnosis of hypoperfusion of resection edges. Undoubtedly, this will reduce the incidence of colorectal anastomotic leaks caused by ischemia of large bowel wall.
Databáze:	MEDLINE
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