Efficacy and Safety of Iris-Claw Intraocular Lens in Pediatric Ectopia Lentis: A Literature Review.

Autor: Yulia DE; Department of Ophthalmology, Faculty of Medicine, University of Indonesia, Cipto Mangunkusumo National Hospital, Jakarta, Indonesia., Soeharto DA; Department of Ophthalmology, Faculty of Medicine, University of Indonesia, Cipto Mangunkusumo National Hospital, Jakarta, Indonesia.
Jazyk: angličtina
Zdroj: Journal of current ophthalmology [J Curr Ophthalmol] 2023 Aug 11; Vol. 35 (1), pp. 1-10. Date of Electronic Publication: 2023 Aug 11 (Print Publication: 2023).
DOI: 10.4103/joco.joco_249_22
Abstrakt: Purpose: To review current evidence regarding the use of iris-claw intraocular lens (IOL) in terms of its efficacy and safety in the population of pediatric ectopia lentis.
Methods: A comprehensive literature search of six electronic databases (PubMed-NCBI, Medline-OVID, Embase, Cochrane, Scopus, and Wiley) and secondary search through reference lists was conducted using keywords selected a priori. All primary studies on the use of iris-claw in pediatric ectopia lentis that evaluated visual acuity (VA), complications, and endothelial cell density (ECD) were included and critically appraised using the Newcastle-Ottawa Scale.
Results: Ten studies were eligible for inclusion with an overall sample size of 168 eyes of children with ectopia lentis, and the majority of studies evaluated anterior iris-claw IOL. All studies reported improvement in postoperative VA. The most commonly reported complication across studies was IOL decentration. All studies reported decreasing ECD, and this was observed in both anterior and retropupillary iris-claw IOL.
Conclusion: Current evidence shows that iris-claw IOL is effective in terms of improving VA in pediatric ectopia lentis. Due to the lack of long-term evidence of its safety in children, one must remain cautious regarding potential endothelial cell loss. Further high-quality, interventional, long-term studies are needed.
Competing Interests: There are no conflicts of interest.
(Copyright: © 2023 Journal of Current Ophthalmology.)
Databáze: MEDLINE
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