Relationship of muscle thickness, strength, and diaphragm function in adults with cystic fibrosis.

Autor:	Uslu NZ; Pulmonary Medicine, Marmara University Medical Faculty, Istanbul, Türkiye., Kocakaya D; Pulmonary Medicine, Marmara University Medical Faculty, Istanbul, Türkiye., Olgun Yıldızeli Ş; Pulmonary Medicine, Marmara University Medical Faculty, Istanbul, Türkiye., Eryüksel E; Pulmonary Medicine, Marmara University Medical Faculty, Istanbul, Türkiye., Keniş Coşkun Ö; Department of Physical Medicine and Rehabilitation, Marmara University Medical Faculty, Istanbul, Türkiye., Cimşit C; Department of Radiology, Marmara University Medical Faculty, Istanbul, Türkiye., Karaketir ŞG; Pulmonary Medicine, Marmara University Medical Faculty, Istanbul, Türkiye., Ceyhan B; Pulmonary Medicine, Marmara University Medical Faculty, Istanbul, Türkiye.
Jazyk:	angličtina
Zdroj:	Turkish journal of physical medicine and rehabilitation [Turk J Phys Med Rehabil] 2022 Dec 02; Vol. 69 (2), pp. 200-206. Date of Electronic Publication: 2022 Dec 02 (Print Publication: 2023).
DOI:	10.5606/tftrd.2023.10361
Abstrakt:	Objectives: This study aimed to evaluate the muscle thickness, strength, and diaphragmatic function and relate them with clinical findings. Patients and Methods: The cross-sectional study was conducted with 54 participants (27 males, 27 females; mean age; 24.5±5.3 years; range, 18 to 45 years) between January 2017 and October 2017. Of the participants, 31 were adult CF patients, and 23 were age-and sex-matched controls. Patient demographics, 6-min walk distance, body mass index (BMI), and fat-free mass index (FFMI) were evaluated. Each patient underwent pulmonary function tests. Quadriceps femoris thickness and diaphragm thickening fraction were assessed by ultrasonography. Upper extremity strength was measured with a handheld dynamometer. Results: There was no difference between the patients' and controls' BMI (p=0.052). However, patients' FFMI was lower than the controls' (p=0.010). The FFMI correlated with pulmonary function tests. Patients' both right and left quadriceps femoris muscles were thinner than the controls (p=0.001 and p=0.001, respectively). Patients with pancreatic insufficiency had thinner muscles than patients without pancreatic insufficiency. The control group had a stronger handgrip than CF patients (33.5±10.1 vs. 24.5±9.2 kg, p=0.003). Conclusion: Peripheral muscle wasting and weakness and lower functional capacity are highly prevalent in CF patients. Competing Interests: Conflict of Interest: The authors declared no conflicts of interest with respect to the authorship and/or publication of this article. (Copyright © 2023, Turkish Society of Physical Medicine and Rehabilitation.)
Databáze:	MEDLINE
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