| Autor: |
Jat RS; School of Chemical Sciences and Pharmacy, Central University of Rajasthan, Ajmer, Rajasthan 305817, India., Bhanuchandra M; School of Chemical Sciences and Pharmacy, Central University of Rajasthan, Ajmer, Rajasthan 305817, India. |
| Jazyk: |
angličtina |
| Zdroj: |
The Journal of organic chemistry [J Org Chem] 2023 Sep 15; Vol. 88 (18), pp. 13184-13190. Date of Electronic Publication: 2023 Sep 05. |
| DOI: |
10.1021/acs.joc.3c01387 |
| Abstrakt: |
Meyer-Schuster rearrangement of 3°-propargyl alcohol to the corresponding α,β-unsaturated carbonyl compounds under SOCl 2 catalysis has been reported. Terminal and internal propargyl alcohols efficiently participated in the reaction. Furthermore, we have demonstrated the synthetic utility of conjugated carbonyl compounds to access densely arene-substituted pyrazolines bearing quaternary centers by reacting with arylhydrazine hydrochloride. Isotopic labeling studies were carried out to gain insights into the reaction mechanism. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
|
