International consensus recommendations on face transplantation: A 2-step Delphi study.

Autor: Longo B; Chair of Plastic Surgery, Department of Surgical Sciences, Tor Vergata University of Rome, Rome, Italy. Electronic address: benedetto.longo@uniroma2.it., Alberti FB; Director of Interface and Director of the Centre for Technology and the Body, King's College London., Pomahac B; Division of Plastic and Reconstructive Surgery, Department of Surgery, Yale New Haven Hospital, Yale School of Medicine, New Haven, Connecticut, USA., Pribaz JJ; Department of Plastic and Reconstructive Surgery, Morsani College of Medicine, University of South Florida, Tampa, Florida, USA., Meningaud JP; Department of Plastic, Reconstructive, and Maxillofacial Surgery, Henri Mondor Hospital, University of Paris, Créteil, France., Lengelé B; Department of Plastic and Reconstructive Surgery, Cliniques Universitaires Saint-Luc, Brussels, Belgium., Özkan Ö; Department of Plastic and Reconstructive Surgery, Akdeniz University School of Medicine, Antalya, Turkey., Özkan Ö; Department of Plastic and Reconstructive Surgery, Akdeniz University School of Medicine, Antalya, Turkey., Barret JP; Department of Plastic Surgery and Burns, Vall d'Hebron Barcelona Hospital Campus, Universidad Autònoma de Barcelona, Barcelona, Spain., Lassus P; Department of Plastic Surgery, Helsinki University Hospital, University of Helsinki, Helsinki, Finland., Blondeel P; Department of Plastic and Reconstructive Surgery, Ghent University Hospital, Ghent, Belgium., Roche N; Department of Plastic and Reconstructive Surgery, Ghent University Hospital, Ghent, Belgium., Gurunian R; Department of Plastic Surgery, Cleveland Clinic Abu Dhabi, Abu Dhabi, United Arab Emirates., Infante-Cossio P; Department of Oral and Maxillofacial Surgery, Virgen del Rocio University Hospital, University of Seville, Seville, Spain., Lindford A; Department of Plastic Surgery, Helsinki University Hospital, University of Helsinki, Helsinki, Finland., Brandacher G; Department of Plastic and Reconstructive Surgery, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA., Giovanoli P; Department of Plastic Surgery and Hand Surgery, University Hospital Zurich, Zurich, Switzerland., Plock J; Department of Plastic Surgery and Hand Surgery, University Hospital Zurich, Zurich, Switzerland., Gorantla VS; Department of Surgery, Wake Forest School of Medicine, Wake Forest Institute of Regenerative Medicine, Winston Salem, North Carolina, USA., Herrington ER; Department of Communication, University of Pittsburgh, Pittsburgh, Pennsylvania, USA., Saleh D; Department of Plastic and Reconstructive Surgery, The Newcastle upon Tyne Hospitals NHS Foundation Trust, Newcastle upon Tyne, UK., Natalwala I; Department of Plastic Surgery, Leeds Teaching Hospitals, Leeds, UK., Cardillo M; Director of National Transplants Center, National Institute of Health, Italian Ministry of Health, Rome, Italy., Jowsey-Gregoire S; Department of Psychiatry and Psychology, Mayo Clinic, Rochester, Minnesota, USA., La Padula S; Department of Plastic, Reconstructive, and Maxillofacial Surgery, Henri Mondor Hospital, University of Paris, Créteil, France; Department of Plastic and Reconstructive Surgery, Università degli Studi di Napoli Federico II, Napoli, Italy., Manas D; NHS Blood and Transplant, Stoke Gifford, Bristol, UK; Liver Transplant Unit, Freeman Hospital, Newcastle Hospitals NHS Foundation Trust, Newcastle University, Newcastle, UK., Benedict J; Center for Global Health Ethics, Duquesne University, Pittsburgh, Pennsylvania, USA., Nuccitelli G; Division of Anesthesia and Intensive Care Medicine, Department of Clinical and Surgical Translational Medicine, Sant'Andrea Hospital, Sapienza University of Rome, Rome, Italy., Bosc R; Department of Plastic, Reconstructive, and Maxillofacial Surgery, Henri Mondor Hospital, University of Paris, Créteil, France., Morello R; Department of Maxillofacial Surgery, Sant'Andrea Hospital, Sapienza University of Rome, Rome, Italy., Farías-Yapur A; School of Psychology, Universidad Panamericana, Benito Juárez, Mexico City, Mexico., Giacalone M; Chair of Plastic Surgery, Department of Surgical Sciences, Tor Vergata University of Rome, Rome, Italy., Hall S; AboutFace, University of York, UK., D'Orsi G; Chair of Plastic Surgery, Department of Surgical Sciences, Tor Vergata University of Rome, Rome, Italy., Cervelli V; Chair of Plastic Surgery, Department of Surgical Sciences, Tor Vergata University of Rome, Rome, Italy.
Jazyk: angličtina
Zdroj: American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons [Am J Transplant] 2024 Jan; Vol. 24 (1), pp. 104-114. Date of Electronic Publication: 2023 Sep 02.
DOI: 10.1016/j.ajt.2023.08.023
Abstrakt: Face transplantation is a viable reconstructive approach for severe craniofacial defects. Despite the evolution witnessed in the field, ethical aspects, clinical and psychosocial implications, public perception, and economic sustainability remain the subject of debate and unanswered questions. Furthermore, poor data reporting and sharing, the absence of standardized metrics for outcome evaluation, and the lack of consensus definitions of success and failure have hampered the development of a "transplantation culture" on a global scale. We completed a 2-round online modified Delphi process with 35 international face transplant stakeholders, including surgeons, clinicians, psychologists, psychiatrists, ethicists, policymakers, and researchers, with a representation of 10 of the 19 face transplant teams that had already performed the procedure and 73% of face transplants. Themes addressed included patient assessment and selection, indications, social support networks, clinical framework, surgical considerations, data on patient progress and outcomes, definitions of success and failure, public image and perception, and financial sustainability. The presented recommendations are the product of a shared commitment of face transplant teams to foster the development of face transplantation and are aimed at providing a gold standard of practice and policy.
(Copyright © 2023 The Authors. Published by Elsevier Inc. All rights reserved.)
Databáze: MEDLINE