Factors Responsible for Worse Outcomes in STEMI Patients With Early vs Delayed Treatment Presenting in a Tertiary Care Center in a Third World Country.

Autor: Ashraf S; Department of Cardiology, Shaikh Zayed Post-Graduate Medical Institute, Lahore, Pakistan., Farooq U; Department of Cardiology, Shaikh Zayed Post-Graduate Medical Institute, Lahore, Pakistan., Shahbaz A; Department of Cardiology, Shaikh Zayed Post-Graduate Medical Institute, Lahore, Pakistan. Electronic address: amirshahbaz89@gmail.com., Khalique F; Department of Medicine, Lahore Medical and Dental College, Lahore, Pakistan., Ashraf M; Department of Cardiology, Shaikh Zayed Post-Graduate Medical Institute, Lahore, Pakistan., Akmal R; Department of Medicine, Lahore Medical and Dental College, Lahore, Pakistan., Siddal MT; Department of Cardiology, Shaikh Zayed Post-Graduate Medical Institute, Lahore, Pakistan., Ashraf M; Department of Pharmacology, King Edward Medical University, Mayo Hospital, Lahore, Pakistan., Ashraf S; Department of Pharmacology, University of Veterinary and Animal Sciences, Lahore, Pakistan., Ashraf S; Department of Pharmacology, University of Veterinary and Animal Sciences, Lahore, Pakistan., Ghufran M; Department of Pharmacology, University of Veterinary and Animal Sciences, Lahore, Pakistan., Akram MK; Department of Pharmacology, University of Veterinary and Animal Sciences, Lahore, Pakistan., Saboor QA; Department of Cardiology, Shaikh Zayed Post-Graduate Medical Institute, Lahore, Pakistan.
Jazyk: angličtina
Zdroj: Current problems in cardiology [Curr Probl Cardiol] 2024 Jan; Vol. 49 (1 Pt B), pp. 102049. Date of Electronic Publication: 2023 Sep 02.
DOI: 10.1016/j.cpcardiol.2023.102049
Abstrakt: The aim of the study is to compare the outcomes among ST-segment elevation myocardial infarction (STEMI) cases with early treatment vs delayed treatment. It was a prospective comparative study on 186 patients with consecutive (nonprobability) sampling. Two groups of cases were made as per their time to get admitted to the hospital (ie, within 2 hours of symptom onset = Group A; after 2 hours of symptom onset = Group B). Patients were asked for factors causing a delay in treatment after the onset of symptoms and were monitored for STEMI outcomes. The mean age of all patients was 46.62 ± 9.76 years and there were 140 (75.27%) male and 46 (24.73%) female, and male to female ratio 3:1.Factors significant for delayed treatment vs nondelayed treatment were poor social economic status (65.6% vs 20.4%), history of chronic stable angina (33.3% vs 11.8%), delayed response in the emergency room (20.4% vs 8.6%), delayed ECG acquisition (26.9% vs 8.6%), delayed ECG interpretation (25.8% vs 4.3%), pain at night 12:00-6:00 AM (21.5% vs 9.7%) and belief that the chest pain is noncardiac (26.9% vs 3.2%). Acute heart failure was significantly greater in group B (9.7%) in comparison with group A (2.2%), re-infarction was 18.3% in group B in comparison with 7.5% group A. Similarly sustained ventricular tachycardia and ventricular fibrillation and in-hospital mortality were higher in group B (12.9%, 14%, and 12.9% respectively). Due to delayed treatment patients had higher hospital stays, and complications, like acute heart failure, re-infarction, ventricular fibrillation, and in-hospital mortality.
Competing Interests: Declaration of Competing Interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.
(Copyright © 2023 Elsevier Inc. All rights reserved.)
Databáze: MEDLINE
Externí odkaz: