Inflammatory Bowel Sugar Disease: A Pause From New Pharmacological Agents and an Embrace of Natural Therapy.

Autor:	Mahmoud A; Internal Medicine, St. Joseph's University Medical Center, Paterson, USA.; Internal Medicine, California Institute of Behavioral Neurosciences & Psychology, Fairfield, USA., Begg M; Internal Medicine, California Institute of Behavioral Neurosciences & Psychology, Fairfield, USA., Tarhuni M; Internal Medicine, California Institute of Behavioral Neurosciences & Psychology, Fairfield, USA., N Fotso M; Internal Medicine, California Institute of Behavioral Neurosciences & Psychology, Fairfield, USA., Gonzalez NA; Internal Medicine, California Institute of Behavioral Neurosciences & Psychology, Fairfield, USA., Sanivarapu RR; Pulmonary and Critical Care Medicine, Texas Tech University Health Sciences Center, Odessa, USA.; Pulmonary and Critical Care Medicine, Nassau University Medical Center, East Meadow, USA.; Internal Medicine, California Institute of Behavioral Neurosciences & Psychology, Fairfield, USA., Osman U; Internal Medicine, California Institute of Behavioral Neurosciences & Psychology, Fairfield, USA.; Geriatrics, Michigan State University College of Human Medicine, East Lansing, USA., Latha Kumar A; Internal Medicine, Spartan Health Sciences University, Vieux Fort, LCA.; Internal Medicine, California Institute of Behavioral Neurosciences & Psychology, Fairfield, USA., Sadagopan A; Internal Medicine, California Institute of Behavioral Neurosciences & Psychology, Fairfield, USA., Alfonso M; Internal Medicine, California Institute of Behavioral Neurosciences & Psychology, Fairfield, USA.
Jazyk:	angličtina
Zdroj:	Cureus [Cureus] 2023 Aug 01; Vol. 15 (8), pp. e42786. Date of Electronic Publication: 2023 Aug 01 (Print Publication: 2023).
DOI:	10.7759/cureus.42786
Abstrakt:	Inflammatory bowel diseases (IBDs), including Crohn's disease and ulcerative colitis, are immune-mediated chronic inflammatory diseases that target the gastrointestinal tract and other distant organs. The incidence of IBDs has been rising and is more prevailing in Western communities. The etiology has been vague, but different theories include environmental factors that elicit an uncontrolled immune response, which damages internal organs. Treatment of either Crohn's disease or ulcerative colitis has witnessed significant advances; however, pharmacological drugs' side effects limit their use. Research about microbiota and its influence on IBDs has gained fame, and multiple studies correlate microbiota diversity positively with IBD treatment. Many factors contribute to the microbiota's health, including different diets, antibiotics, prebiotics, probiotics, synbiotics, and postbiotics. Specific immune responses lie behind the pathogenesis of IBDs and microbiota dysbiosis, and different studies have postulated new ways to control this abnormal response. Physical activity, sun exposure, efficient sleep, intermittent fasting, and supplementation of probiotics and vitamins are natural ways that help modulate this immune response, do not cost money as IBD pharmacological drugs, and do not come with deleterious side effects that are sometimes more harmful than IBDs. Our article proposes a comprehensive natural approach that can benefit IBD patients enormously. This approach does not replace the medications currently used in treating IBDs. The suggested approach can be used in combination with medications and might aid in reducing the doses of those medications. Competing Interests: The authors have declared that no competing interests exist. (Copyright © 2023, Mahmoud et al.)
Databáze:	MEDLINE
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