An unusually high prevalence of isolated prostatic ductal adenocarcinoma among Saudi patients: A registry-based study.

Autor: Alasker A; Department of Urology, College of Medicine, King Saud Bin Abdulaziz University for Health Sciences, Riyadh, Saudi Arabia.; King Abdullah International Medical Research Center, Riyadh, Saudi Arabia.; Department of Urology, King Abdulaziz Medical City, Riyadh, Saudi Arabia., Alghafees M; Department of Urology, College of Medicine, King Saud Bin Abdulaziz University for Health Sciences, Riyadh, Saudi Arabia., Chaudhri EN; Department of Medicine, College of Medicine, Alfaisal University, Riyadh, Saudi Arabia., Al Qurashi AA; King Abdullah International Medical Research Center, Riyadh, Saudi Arabia.; Department of Medicine, College of Medicine, King Saud Bin Abdulaziz University for Health Sciences, Jeddah, Saudi Arabia., Abdul Rab S; Department of Medicine, College of Medicine, Alfaisal University, Riyadh, Saudi Arabia., Sabbah BN; Department of Medicine, College of Medicine, Alfaisal University, Riyadh, Saudi Arabia., Musalli Z; Department of Urology, King Abdulaziz Medical City, Riyadh, Saudi Arabia., Alyami A; Department of Urology, King Abdulaziz Medical City, Riyadh, Saudi Arabia.
Jazyk: angličtina
Zdroj: Urology annals [Urol Ann] 2023 Jul-Sep; Vol. 15 (3), pp. 320-324. Date of Electronic Publication: 2023 Jul 17.
DOI: 10.4103/ua.ua_46_23
Abstrakt: Objective: We conduct a secondary analysis on the demographics, tumor characteristics, survival, and risk factors for mortality among patients with prostatic ductal adenocarcinoma (PDA) in the Kingdom of Saudi Arabia (KSA).
Methods: This is a registry-based retrospective study that included all patients diagnosed with prostate cancer in the KSA. The data were collected from the Saudi Cancer Registry, which collects tumor data from all private, military, and health ministry hospitals in Saudi Arabia through five regional offices.
Results: Among 3607 prostate cancer patients detected during the specified period, 209 (5.8%) had ductal adenocarcinoma. The median interquartile range age of patients was 72.0 years (64.0-78.0). Adenocarcinoma lesions were malignant among all the patients. Grade III tumors were most frequently apparent lesions (61.2%), followed by Grade II tumors (26.3%), Grade I tumors (7.2%), and Grade VI tumors (5.3%). A total of 33 patients died, representing 15.8% of the whole sample. The 1-year survival rate was 78.1%. More than a third of patients who were residing in the Western region deceased (38.0%), whereas no deaths were reported in other regions with a statistically significant difference based on regions ( P < 0.001).
Conclusion: To the best of our knowledge, this is the first registry-based study to investigate PDA in the KSA; these efforts were done to further understand this deadly condition and to further enhance patient care in the KSA.
Competing Interests: There are no conflicts of interest.
(Copyright: © 2023 Urology Annals.)
Databáze: MEDLINE
Externí odkaz: