Sociodemographic disparities associated with advanced stages and distant metastatic breast cancers at diagnosis in Indonesia: a cross-sectional study.

Autor:	Setyawan IB; Perhimpunan Bedah Onkologi Indonesia (PERABOI)/Indonesian Association of Surgical Oncology (ISSO).; Division of Surgical Oncology, RSUP Dr IGNG Ngoerah/Udayana University, Denpasar, Bali., Kurnia D; Perhimpunan Bedah Onkologi Indonesia (PERABOI)/Indonesian Association of Surgical Oncology (ISSO).; Division of Surgical Oncology, RSUD Dr M. Yunus Bengkulu, Kota Bengkulu, Bengkulu., Setiaji K; Perhimpunan Bedah Onkologi Indonesia (PERABOI)/Indonesian Association of Surgical Oncology (ISSO).; Division of Surgical Oncology, RSUP Dr Sardjito / Universitas Gadjah Mada, Yogyakarta., Anwar SL; Perhimpunan Bedah Onkologi Indonesia (PERABOI)/Indonesian Association of Surgical Oncology (ISSO).; Division of Surgical Oncology, RSUP Dr Sardjito / Universitas Gadjah Mada, Yogyakarta., Purwanto DJ; Perhimpunan Bedah Onkologi Indonesia (PERABOI)/Indonesian Association of Surgical Oncology (ISSO).; Division of Surgical Oncology, RSK Dharmais, Jakarta 11420, DKI Jakarta., Azhar Y; Perhimpunan Bedah Onkologi Indonesia (PERABOI)/Indonesian Association of Surgical Oncology (ISSO).; Division of Surgical Oncology, RSUP Dr Hasan Sadikin / Universitas Padjadjaran, Bandung, Jawa Barat., Budijitno S; Perhimpunan Bedah Onkologi Indonesia (PERABOI)/Indonesian Association of Surgical Oncology (ISSO).; Division of Surgical Oncology, RSUP Dr Kariadi / Universitas Diponegoro, Semarang, Jawa Tengah., Suprabawati DGA; Perhimpunan Bedah Onkologi Indonesia (PERABOI)/Indonesian Association of Surgical Oncology (ISSO).; Division of Surgical Oncology, RSUD Dr Soetomo / Universitas Airlangga, Surabaya, Jawa Timur., Priyono SH; Perhimpunan Bedah Onkologi Indonesia (PERABOI)/Indonesian Association of Surgical Oncology (ISSO).; Division of Surgical Oncology, Universitas Lambung Mangkurat, Banjarmasin, Kalimantan Selatan., Siregar BA; Perhimpunan Bedah Onkologi Indonesia (PERABOI)/Indonesian Association of Surgical Oncology (ISSO).; Division of Surgical Oncology, RSUD Dr H Abdul Moeloek / Universitas Lampung, Bandar Lampung, Lampung., Indriawan R; Perhimpunan Bedah Onkologi Indonesia (PERABOI)/Indonesian Association of Surgical Oncology (ISSO).; Division of Surgical Oncology, RSUD Propinsi NTB / Universitas Mataram, Kota Mataram, Nusa Tenggara Barat., Tripriadi ES; Perhimpunan Bedah Onkologi Indonesia (PERABOI)/Indonesian Association of Surgical Oncology (ISSO).; Division of Surgical Oncology, RSUD Dr Arifin Achmad / Universitas Riau, Pekanbaru, Riau., Umar M; Perhimpunan Bedah Onkologi Indonesia (PERABOI)/Indonesian Association of Surgical Oncology (ISSO).; Division of Surgical Oncology, RSUP Dr Moh Hoesain / Universitas Sriwijaya, Palembang, Sumatra Selatan., Pieter JS; Perhimpunan Bedah Onkologi Indonesia (PERABOI)/Indonesian Association of Surgical Oncology (ISSO).; Division of Surgical Oncology, RSUP Dr Wahidin Sudirohusodo / Universitas Hasanuddin, Makassar, Sulawesi Selatan., Yarso KY; Perhimpunan Bedah Onkologi Indonesia (PERABOI)/Indonesian Association of Surgical Oncology (ISSO).; Division of Surgical Oncology, RSUD Dr Moewardi / Universitas Sebelas Maret, Surakarta, Jawa Tengah., Hermansyah D; Perhimpunan Bedah Onkologi Indonesia (PERABOI)/Indonesian Association of Surgical Oncology (ISSO).; Division of Surgical Oncology, RSUP Dr H Adam Malik / Universitas Sumatra Utara, Medan, Sumatra Utara., Wibisana IG; Perhimpunan Bedah Onkologi Indonesia (PERABOI)/Indonesian Association of Surgical Oncology (ISSO).; Division of Surgical Oncology, RSUP Dr Cipto Mangunkusumo / Universitas Indonesia, Padang, Sumatra Barat., Harahap WA; Perhimpunan Bedah Onkologi Indonesia (PERABOI)/Indonesian Association of Surgical Oncology (ISSO).; Division of Surgical Oncology, RSUP Dr M Djamil / Universitas Andalas, Jakarta, DKI Jakarta, Indonesia., Gautama W; Perhimpunan Bedah Onkologi Indonesia (PERABOI)/Indonesian Association of Surgical Oncology (ISSO).; Division of Surgical Oncology, RSK Dharmais, Jakarta 11420, DKI Jakarta., Achmad D; Perhimpunan Bedah Onkologi Indonesia (PERABOI)/Indonesian Association of Surgical Oncology (ISSO).; Division of Surgical Oncology, RSUP Dr Hasan Sadikin / Universitas Padjadjaran, Bandung, Jawa Barat.
Jazyk:	angličtina
Zdroj:	Annals of medicine and surgery (2012) [Ann Med Surg (Lond)] 2023 Aug 01; Vol. 85 (9), pp. 4211-4217. Date of Electronic Publication: 2023 Aug 01 (Print Publication: 2023).
DOI:	10.1097/MS9.0000000000001030
Abstrakt:	Background: The global health burden of breast cancer is increasing with 5-year survival rates being much shorter in low-income and middle-income countries. Sociodemographic and clinical disparities in early cancer detection affect long-term outcome. Methods: The authors compared social, demographic, and pathological characteristics associated with metastatic and late stages of breast cancer diagnosis using data collected from a special registry developed by Perhimpunan Bedah Onkologi Indonesia (PERABOI) in 2015. Results: Of 4959 patients recruited in this study, 995 women (20.1%) were diagnosed with metastatic breast cancer. Lower education status and living in rural areas were significantly associated with Stage IV at diagnosis [odds ratio (OR)=1.256, 95% CI=1.093-1.445, P =0.001; and OR=1.197, 95% CI=1.042-1.377, P =0.012; respectively). Main complaints other than lump (ulceration, breast pain, and discharge) and occupation as a housewife were also associated with the presentation of metastatic diseases (OR=2.598, 95% CI=2.538-3.448, P< 0.001 and OR=1.264, 95% CI=1.056-1.567, P =0.030, respectively). Having lower education and living outside Java and Bali islands were associated with the diagnosis of late-stage breast cancers (OR=1.908, 95% CI=1.629-2.232, P< 0.001 and OR=3.039, 95% CI=2.238-4.126, P <0.001; respectively). A higher proportion of breast cancer patients were relatively younger with bigger tumour size, positive axillary nodal involvement, and more frequent Human epidermal growth factor receptor 2 overexpression. Conclusion: The authors identified sociodemographic disparities in the metastatic and late-stage diagnosis of breast cancers among Indonesian women. The subsequent action is required to reduce disparities faced by women with lower social and educational levels for early diagnosis and better healthcare access. Competing Interests: The authors declare that they have no conflicts of interest.Sponsorships or competing interests that may be relevant to content are disclosed at the end of this article. (Copyright © 2023 The Author(s). Published by Wolters Kluwer Health, Inc.)
Databáze:	MEDLINE
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