Efficacy of opioid-free anesthesia in modified radical mastectomy: a cross-sectional observational study.

Autor:	Assaf GR; Department of Anesthesiology., Yared F; Department of Internal Medicine., Dib MJ; Department of Anesthesiology., Mouawad T; Department of Anesthesiology., Tarabay O; Department of Neurology., Noujeim JP; Department of Urology., El-Helou E; Department of General Surgery, Lebanese Hospital Geitaoui - University Medical Center, Beirut, Lebanon., Kaady J; Department of Anesthesiology., Abboud B; Department of General Surgery, Lebanese Hospital Geitaoui - University Medical Center, Beirut, Lebanon.
Jazyk:	angličtina
Zdroj:	Annals of medicine and surgery (2012) [Ann Med Surg (Lond)] 2023 Aug 03; Vol. 85 (9), pp. 4289-4292. Date of Electronic Publication: 2023 Aug 03 (Print Publication: 2023).
DOI:	10.1097/MS9.0000000000000718
Abstrakt:	Introduction: Perioperative management of female patients undergoing breast surgeries differs from other patients due to chronic pain and postoperative nausea and vomiting. The anesthesia could consist of opioid-free general anesthesia (OFA) or non-opioid-free general anesthesia (NOFA). OFA relies on multimodal analgesia preoperatively and postoperatively. However, it is not yet established whether OFA could replace NOFA as a standard regimen for the management of breast surgeries. The aim of this study is to evaluate the efficacy of OFA for breast surgeries in female patients. Materials and Methods: Patients undergoing modified radical mastectomy were retrospectively recruited. Two groups were defined: group 1, consisting of treated patients using OFA and group 2, consisting of treated patients using NOFA. Mean time to extubate and mean dose of morphine after recovery were computed. Postoperative morphine and antiemetic use were assessed for up to 24 h. A comparison of the computed data was conducted between both groups. Results: A total of 116 patients were included with a mean age of 53±13 years. Group 1 consisted of 56 (mean age was 54±14 years). Group 2 consisted of 60 patients (mean age was 51±12 years). Demographic parameters and time to extubate did not yield significant differences. We noticed morphine sparing at T0 and T12 with statistically significant differences P =0.043 and P =0.006, respectively. Conclusion: OFA could be considered in modified radical mastectomy management in female patients; nerve block seemed to act as morphine sparing in operative and postoperative settings by providing significantly less time to extubate with less postoperative morphine requirement. Competing Interests: The authors declare that they have no conflicts of interest.Sponsorships or competing interests that may be relevant to content are disclosed at the end of this article. (Copyright © 2023 The Author(s). Published by Wolters Kluwer Health, Inc.)
Databáze:	MEDLINE
Externí odkaz:	Zobrazit plný text záznamu