Saliva sampling strategies affecting the salivary glucose measurement.

Autor: Qian X; Medical School, Sun Yat-Sen University, Guangzhou, China.; Renaissance Bio, New Territories, Hong Kong SAR, China. c.liao@uqconnect.edu.au., Ko A; Renaissance Bio, New Territories, Hong Kong SAR, China. c.liao@uqconnect.edu.au., Li H; Shenzhen People's Hospital, Shenzhen, China., Liao C; Renaissance Bio, New Territories, Hong Kong SAR, China. c.liao@uqconnect.edu.au.
Jazyk: angličtina
Zdroj: Analytical methods : advancing methods and applications [Anal Methods] 2023 Sep 14; Vol. 15 (35), pp. 4598-4605. Date of Electronic Publication: 2023 Sep 14.
DOI: 10.1039/d3ay01005h
Abstrakt: Characterized by sustained elevated blood glucose levels, diabetes mellitus has become one of the largest global public health concerns by imposing a heavy global burden on socio-economic development. To date, regular blood glucose level check by performing a finger-prick test has been a routine strategy to monitor diabetes. However, the intrusive nature of finger blood prick tests makes it challenging for individuals to maintain consistent testing routines. Recently, salivary glucose measurement (SGM) has increasingly become a non-invasive alternative to traditional blood glucose testing for diabetes. Despite that, further research is needed to standardize the collection methods and address the issues of variability to ensure accurate and reliable SGM. To resolve possible remaining issues in SGM, we here thoroughly explored saliva sampling strategies that could impact the measurement results. Additionally, the effects of supplements taken, mouth washing, gum chewing, and smoking were collectively analyzed, followed by a continuous SGM over a long period, forming the stepping stone for the practical transitional development of SGM in non-invasive diabetes monitoring.
Databáze: MEDLINE