Clinical and Radiographic Evaluation of Autologous Platelet-Rich Fibrin With or Without Demineralized Bone Matrix in the Treatment of Grade II Furcation Defects.
Autor: | Patel B; Periodontology, Karnavati School of Dentistry, Karnavati University, Gandhinagar, IND., Joshi S; Periodontology, Karnavati School of Dentistry, Karnavati University, Gandhinagar, IND., Nagrani T; Periodontology, Karnavati School of Dentistry, Karnavati University, Gandhinagar, IND., Girdhar GA; Periodontology, Karnavati School of Dentistry, Karnavati University, Gandhinagar, IND., Patel H; Periodontology, Karnavati School of Dentistry, Karnavati University, Gandhinagar, IND., Sinha S; Physiology, Khulna City Medical College Hospital, Khulna, BGD., Haque M; Karnavati Scientific Research Center, Karnavati School of Dentistry, Karnavati University, Gandhinagar, IND.; Pharmacology and Therapeutics, National Defence University of Malaysia, Kuala Lumpur, MYS., Kumar S; Periodontology, Karnavati School of Dentistry, Karnavati University, Gandhinagar, IND., Haq MA; Biostatistics, Infectious Diseases Division, International Centre for Diarrhoeal Disease Research, Bangladesh (ICDDRB), Dhaka, BGD. |
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Jazyk: | angličtina |
Zdroj: | Cureus [Cureus] 2023 Aug 30; Vol. 15 (8), pp. e44394. Date of Electronic Publication: 2023 Aug 30 (Print Publication: 2023). |
DOI: | 10.7759/cureus.44394 |
Abstrakt: | Introduction This study aims to differentiate the employment of demineralized bone matrix (DMBM; Osseograft, Advanced Biotech Products (P) Ltd, Chennai, India) and platelet-rich fibrin (PRF) alone to a composite graft consisting of both materials in the surgical actions toward the anomalies of the human periodontal furcation imperfection. Methods In a split-mouth study, 30 patients with mandibular molars affected by the furcation were allocated without conscious choice to test (PRF + DMBM, n = 30) or control (PRF, n = 30) categories. At the starting point, three months after surgery, and six months later, the following modifiable factors were evaluated: probing pocket depth (PPD), full-mouth plaque scores, full-mouth gingival scores, radiographic defect depth, relative vertical clinical attachment level (RVCAL), and relative horizontal clinical attachment level (RHCAL). Results Results at three and six months demonstrated substantial differences between baseline values for both treatment methods in clinical and X-ray imaging appraisal. Nonetheless, the PRF/DMBM group manifests statistically significantly soaring changes observed in comparison to the PRF group. Overall, the probing depth (PD) in the test site was significantly lower than that in the control site, showing a reduction of 68% (95% CI=41%, 95%, p<0.001). Conclusion Clinical indications significantly improved with PRF and DMBM combined instead of PRF alone. On radiographs, the test group also showed higher bone fill. Competing Interests: The authors have declared that no competing interests exist. (Copyright © 2023, Patel et al.) |
Databáze: | MEDLINE |
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