Association of the high-sensitive cardiac troponin T levels and long-term mortality in patients with acute aortic dissection type A.

Autor:	Jenab Y; Tehran Heart Center, Tehran University of Medical Sciences, Tehran, Iran., Ahmadi-Tafti SH; Department of Cardiac Surgery, Tehran University of Medical Sciences, Tehran, Iran., Davarpasand T; Tehran Heart Center, Tehran University of Medical Sciences, Tehran, Iran., Jalali A; Tehran Heart Center, Tehran University of Medical Sciences, Tehran, Iran., Khederlou H; Tehran Heart Center, Tehran University of Medical Sciences, Tehran, Iran.
Jazyk:	angličtina
Zdroj:	Journal of cardiovascular and thoracic research [J Cardiovasc Thorac Res] 2023; Vol. 15 (2), pp. 116-120. Date of Electronic Publication: 2023 Jun 29.
DOI:	10.34172/jcvtr.2023.31624
Abstrakt:	Introduction: Acute aortic dissection type A is a life-threatening cardiovascular emergency necessitating rapid diagnosis and treatment. We sought a new prognostic tool with cardiac biomarkers and simple inflammatory factors. Methods: from 2003 to 2014, 50 patients with documented acute aortic dissection type A were entered to this study. These patients were followed up until December 2020; within median follow up of 93.6 months. The patients were evaluated on the association of the baseline characteristics, first laboratory investigation, echocardiographic findings, surgical approach, and long-term mortality. Results: Total number of mortality during the follow up was 29 (58%) patients, which was significantly higher in medical group (89.4% vs 38.7%, P value=0.001). Multivariable analysis showed only an increase in hs-cTnT levels was suggested as a predictor of mortality (95% CI: 1.06-1.38; HR=1.21; P =0.005), so that for every 100 units increase, patients were 21% more likely to have mortality in long term. Also, performing surgical treatment for aortic dissection was determined as the independent predictor of surviving, so that death was 74.6% less than those who received medical treatment (95% CI: 0.13-0.58; HR=0.27; P =0.001). Conclusion: hs-cTnT is a potential predictor of mortality in patients with acute aortic dissection type A. Competing Interests: The authors declare that they have not competing financial interests or personal relationships that could have influenced the work reported in this paper. (© 2023 The Author(s).)
Databáze:	MEDLINE
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