Morphometric Shape Analysis of Corpus Callosum in Children With Down Syndrome.
| Autor: | Erdemli Gürsel B; Department of Radiology, Bursa Uludağ University Faculty of Medicine, Bursa, Turkey., Ercan İ; Department of Biostatistics, Bursa Uludağ University Faculty of Medicine, Bursa, Turkey., Şahin İ; Department of Biostatistics, Bursa Uludağ University Institute of Health Sciences, Bursa, Turkey., Öngen G; Department of Radiology, Bursa Uludağ University Faculty of Medicine, Bursa, Turkey. |
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| Jazyk: | angličtina |
| Zdroj: | Clinical pediatrics [Clin Pediatr (Phila)] 2024 Jun; Vol. 63 (6), pp. 815-821. Date of Electronic Publication: 2023 Aug 31. |
| DOI: | 10.1177/00099228231196933 |
| Abstrakt: | Down syndrome (DS) is characterized by varying degrees of mental retardation and delay in neurocognitive functions. Herein, we analyzed the morphometric shape of the corpus callosum (CC) in children with DS. Twenty-three DS cases underwent magnetic resonance imaging and have grossly normal CC, and 23 control group cases were included in this retrospective study (2012-2020). The CC was obtained from T2-weighted mid-sagittal images, and certain anatomical points were marked on the CC. Statistical geometric shapes and deformations of CC were evaluated for both groups. The age range of patients with DS and control group was 6 to 42 months. A statistically significant difference was found in the shape of CC between the groups ( P < .001). Deformation was most evident in the splenium in the DS group. Competing Interests: Declaration of Conflicting InterestsThe author(s) declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article. |
| Databáze: | MEDLINE |
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