Disparities in outcomes of COVID-19 hospitalizations in native American individuals.

Autor:	Bime C; Division of Pulmonary, Allergy, Critical Care & Sleep Medicine, Department of Medicine, University of Arizona, Tucson, AZ, United States., Wang Y; Department of Informatics Technology, Banner Health, Phoenix, AZ, United States., Carr G; Division of Pulmonary, Allergy, Critical Care & Sleep Medicine, Department of Medicine, University of Arizona, Tucson, AZ, United States.; Department of Medicine, University of Arizona College of Medicine, Tucson, AZ, United States., Swearingen D; Department of Biomedical Informatics, University of Arizona College of Medicine, Phoenix, AZ, United States.; Department of Medical Informatics, Banner Health, Phoenix, AZ, United States., Kou S; Department of Informatics Technology, Banner Health, Phoenix, AZ, United States., Thompson P; Department of Academic and Facilities Research, Banner Health, Phoenix, AZ, United States., Kusupati V; Division of General Internal Medicine, Department of Medicine, University of Arizona, Tucson, AZ, United States., Parthasarathy S; Division of Pulmonary, Allergy, Critical Care & Sleep Medicine, Department of Medicine, University of Arizona, Tucson, AZ, United States.
Jazyk:	angličtina
Zdroj:	Frontiers in public health [Front Public Health] 2023 Aug 15; Vol. 11, pp. 1220582. Date of Electronic Publication: 2023 Aug 15 (Print Publication: 2023).
DOI:	10.3389/fpubh.2023.1220582
Abstrakt:	Objectives: This study aimed to investigate COVID-19-related disparities in clinical presentation and patient outcomes in hospitalized Native American individuals. Methods: The study was performed within 30 hospitals of the Banner Health system in the Southwest United States and included 8,083 adult patients who tested positive for SARS-CoV-2 infection and were hospitalized between 1 March 2020 and 4 September 2020. Bivariate and multivariate analyses were used to assess racial and ethnic differences in clinical presentation and patient outcomes. Results: COVID-19-related hospitalizations in Native American individuals were over-represented compared with non-Hispanic white individuals. Native American individuals had fewer symptoms at admission; greater prevalence of chronic lung disease in the older adult; two times greater risk for ICU admission despite being younger; and 20 times more rapid clinical deterioration warranting ICU admission. Compared with non-Hispanic white individuals, Native American individuals had a greater prevalence of sepsis, were more likely to require invasive mechanical ventilation, had a longer length of stay, and had higher in-hospital mortality. Conclusion: Native American individuals manifested greater case-fatality rates following hospitalization than other races/ethnicities. Atypical symptom presentation of COVID-19 included a greater prevalence of chronic lung disease and a more rapid clinical deterioration, which may be responsible for the observed higher hospital mortality, thereby underscoring the role of pulmonologists in addressing such disparities. Competing Interests: The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest. (Copyright © 2023 Bime, Wang, Carr, Swearingen, Kou, Thompson, Kusupati and Parthasarathy.)
Databáze:	MEDLINE
Externí odkaz:	Zobrazit plný text záznamu