The COMBAT project: controlling and progressively minimizing the burden of vector-borne animal trypanosomosis in Africa.

Autor:	Boulangé A; CIRAD, UMR INTERTRYP, Bouaké, 01 BP 1500, Cote d'Ivoire.; CIRAD, IRD, INTERTRYP, Univ of Montpellier, Montpellier, F-34398, France., Lejon V; CIRAD, IRD, UMR INTERTRYP, Univ of Montpellier, Montpellier, F-34398, France., Berthier D; CIRAD, IRD, INTERTRYP, Univ of Montpellier, Montpellier, F-34398, France.; CIRAD, UMR INTERTRYP, Montpellier, F-34398, France., Thévenon S; CIRAD, IRD, INTERTRYP, Univ of Montpellier, Montpellier, F-34398, France.; CIRAD, UMR INTERTRYP, Montpellier, F-34398, France., Gimonneau G; CIRAD, IRD, INTERTRYP, Univ of Montpellier, Montpellier, F-34398, France.; CIRAD, UMR INTERTRYP, Dakar-Hann, BP 2057, Senegal., Desquesnes M; CIRAD, IRD, INTERTRYP, Univ of Montpellier, Montpellier, F-34398, France.; CIRAD, UMR INTERTRYP, Toulouse, F-31076, France., Abah S; Mission Spéciale D'Eradication des Glossines (MSEG), Ministère de l'Elevage, des Pêches et des Industries Animales, Ngaoundéré, BP 263, Cameroon., Agboho P; Centre International de Recherche-Développement sur l'Elevage en zone Subhumide (CIRDES), Bobo-Dioulasso, 01 BP 454, Burkina Faso., Chilongo K; Tsetse and Trypanosomosis Control Unit (TTCU), Ministry of Fisheries and Livestock, P.O Box 50197, Lusaka, 10101, Zambia., Gebre T; National Institute for Control and Eradication of Tsetse and Trypanosomosis (NICETT), P.O Box 19917, Addis Ababa, Ethiopia., Fall AG; Institut Sénégalais de Recherches Agricoles (ISRA), Dakar-Hann, BP 2057, Senegal., Kaba D; Institut Pierre Richet (IPR), Institut National de Santé Publique, Bouaké, 01 BP 1500, Cote d'Ivoire., Magez S; Laboratory of Cellular and Molecular Immunology, Vrije Universiteit Brussel (VUB), Brussels, B-1050, Belgium., Masiga D; International Centre of Insect Physiology and Ecology (ICIPE), Nairobi, 00100, Kenya., Matovu E; Makerere University, Kampala, 10218, Uganda., Moukhtar A; Institut de Recherche en Elevage pour le Développement (IRED), N'Djamena, Route de Farcha, BP 433, Chad., Neves L; Centro de Biotecnologia, Universidade Eduardo Mondlane, Maputo, 00200, Mozambique.; Department of Veterinary Tropical Diseases, Faculty of Veterinary Sciences, University of Pretoria, Onderstepoort, 0110, South Africa., Olet PA; Kenya Tsetse and Trypanosomosis Eradication Council (KENTTEC), Nairobi, 00800, Kenya., Pagabeleguem S; Insectarium de Bobo-Dioulasso - Campagne d'Eradication de la mouche Tsé-tsé et de la Trypanosomose (IBD-CETT), Ministère des ressources animales et halieutiques, Bobo-Dioulasso, 01 BP 1087, Burkina Faso., Shereni W; Division of Tsetse Control Services (TCD), Ministry of Lands, Agriculture, Fisheries, Water and Rural Development, P.O Box CY52, Harare, Zimbabwe., Sorli B; Institut d'Electronique et des Systèmes (IES), Université de Montpellier, Montpellier, F-34090, France., Taioe MO; Onderstepoort Veterinary Research, Agricultural Research Council (ARC), Pretoria, 0110, South Africa., Tejedor Junco MT; Universidad de Las Palmas de Gran Canaria (ULPGC), Las Palmas de Gran Canaria, 35016, Spain., Yagi R; Central Veterinary Research Laboratory (CVRL), Animal Resources Research Corporation, Khartoum, 12217, Sudan., Solano P; CIRAD, IRD, UMR INTERTRYP, Univ of Montpellier, Montpellier, F-34398, France., Cecchi G; Animal Production and Health Division, Food and Agriculture Organization of the United Nations (FAO), Rome, 00153, Italy.
Jazyk:	angličtina
Zdroj:	Open research Europe [Open Res Eur] 2022 Aug 15; Vol. 2, pp. 67. Date of Electronic Publication: 2022 Aug 15 (Print Publication: 2022).
DOI:	10.12688/openreseurope.14759.2
Abstrakt:	Vector-borne diseases affecting livestock have serious impacts in Africa. Trypanosomosis is caused by parasites transmitted by tsetse flies and other blood-sucking Diptera . The animal form of the disease is a scourge for African livestock keepers, is already present in Latin America and Asia, and has the potential to spread further. A human form of the disease also exists, known as human African trypanosomosis or sleeping sickness. Controlling and progressively minimizing the burden of animal trypanosomosis (COMBAT) is a four-year research and innovation project funded by the European Commission, whose ultimate goal is to reduce the burden of animal trypanosomosis (AT) in Africa. The project builds on the progressive control pathway (PCP), a risk-based, step-wise approach to disease reduction or elimination. COMBAT will strengthen AT control and prevention by improving basic knowledge of AT, developing innovative control tools, reinforcing surveillance, rationalizing control strategies, building capacity, and raising awareness. Knowledge gaps on disease epidemiology, vector ecology and competence, and biological aspects of trypanotolerant livestock will be addressed. Environmentally friendly vector control technologies and more effective and adapted diagnostic tools will be developed. Surveillance will be enhanced by developing information systems, strengthening reporting, and mapping and modelling disease risk in Africa and beyond. The socio-economic burden of AT will be assessed at a range of geographical scales. Guidelines for the PCP and harmonized national control strategies and roadmaps will be developed. Gender equality and ethics will be pivotal in all project activities. The COMBAT project benefits from the expertise of African and European research institutions, national veterinary authorities, and international organizations. The project consortium comprises 21 participants, including a geographically balanced representation from 13 African countries, and it will engage a larger number of AT-affected countries through regional initiatives. Competing Interests: No competing interests were disclosed. (Copyright: © 2022 Boulangé A et al.)
Databáze:	MEDLINE
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