Multifocal visual evoked potential for evaluation of open-angle glaucoma.

Autor:	Afify MEHM; Ophthalmology Department, Ain Shams University Hospitals, Cairo, Egypt., Abdelgawad RHA; Ophthalmology Department, Ain Shams University Hospitals, Cairo, Egypt., Hamdi MM; Ophthalmology Department, Ain Shams University Hospitals, Cairo, Egypt., El-Shazly AAE; Ophthalmology Department, Ain Shams University Hospitals, Cairo, Egypt., Abdelshafik MA; Ophthalmology Department, Ain Shams University Hospitals, Cairo, Egypt.
Jazyk:	angličtina
Zdroj:	Medical hypothesis, discovery & innovation ophthalmology journal [Med Hypothesis Discov Innov Ophthalmol] 2021 Nov 17; Vol. 10 (3), pp. 114-120. Date of Electronic Publication: 2021 Nov 17 (Print Publication: 2021).
DOI:	10.51329/mehdiophthal1429
Abstrakt:	Background: To correlate multifocal visual evoked potential (mfVEP) findings with static automated perimetry (SAP) and spectral-domain optical coherence tomography (SD-OCT) in eyes with primary open- angle glaucoma (POAG). Methods: This cross-sectional study included a consecutive sample of 40 eyes of 40 patients with POAG. The participants underwent a complete ophthalmologic assessment, axial length (AL) measurement, and assessments with SAP, SD-OCT, and mfVEP. Results: POAG cases were aged 49.70 (14.16) years (mean [SD]) and most were females (n = 24, 60%). For eyes of patients with POAG, the mfVEP upper-ring signal-to-noise ratio (SNR) showed a significant negative correlation with best-corrected logMAR visual acuity (r = - 0.33; P = 0.038), and a significant positive correlation with the superior hemifield of the visual field (VF) and the inferior-quadrant retinal nerve fiber layer (RNFL) thickness (r = + 0.34; P = 0.030; r = + 0.51; P < 0.001, respectively). Similarly, the mfVEP lower-ring SNR showed a significant negative correlation with best-corrected logMAR visual acuity (r = - 0.36; P = 0.024) and a significant positive correlation with the inferior hemifield of the VF and superior quadrant RNFL thickness (r = + 0.55; P < 0.001 and r = + 0.70; P < 0.001, respectively). Conclusions: mfVEP is a promising tool for objective assessment of the VF in patients with POAG, as it is positively correlated with the VF and OCT RNFL thickness. Future longitudinal studies with a larger sample size and a specific glaucoma subtype, along with multiple follow-up evaluations, are warranted to confirm our preliminary results. Competing Interests: None. (© Author(s).)
Databáze:	MEDLINE
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