[Nanotechnologies in ophthalmology].

Autor: Gusev AA; Tambov State University named after G.R. Derzhavin, Tambov, Russia.; National University of Science and Technology (MISIS), Moscow, Russia., Zakharova OV; Tambov State University named after G.R. Derzhavin, Tambov, Russia.; National University of Science and Technology (MISIS), Moscow, Russia.; Plekhanov Russian University of Economics, Moscow, Russia., Vasyukova IA; Tambov State University named after G.R. Derzhavin, Tambov, Russia., Osmanov RE; Tambov branch of S.N. Fedorov National Medical Research Center 'MNTK 'Eye Microsurgery', Tambov, Russia., Al-Makhdar YM; Krasnov Research Institute of Eye Diseases, Moscow, Russia.
Jazyk: ruština
Zdroj: Vestnik oftalmologii [Vestn Oftalmol] 2023; Vol. 139 (4), pp. 107-114.
DOI: 10.17116/oftalma2023139041107
Abstrakt: Application of new materials and methods in the diagnosis and treatment of eye diseases is one of the promising research areas in modern ophthalmology. Significant progress has been made in understanding the pathogenesis, diagnosis and treatment of eye diseases using nanotechnologies and nanomaterials. This paper presents the main achievements and results of original research on this issue. It has been shown that nanoparticles are able to overcome biological barriers, deliver drugs to the target site, and provide the required drug release rate. Modern nanotechnological approaches in tissue engineering are also being actively introduced into ophthalmology, making it possible to create nanoframeworks for growing three-dimensional cellular structures, including arrays of pigment epithelium cells and retinal ganglion cells for the treatment of retinal damage caused by degenerative diseases, injuries and infections.
Databáze: MEDLINE