Neurological Involvements in COVID-19: A hospital-based study.

Autor:	Montazerlotfelahi H; Department of Pediatric Neurology, Imam Ali Hospital, Faculty of Medicine, Alborz University of medical sciences, Karaj, Iran., Norouzi M; Department of the Pediatrics, Imam Ali Hospital, Faculty of Medicine, Alborz University of Medical Sciences, Karaj, Iran., Askarimoghaddam F; Department of the Pediatrics, Imam Ali Hospital, Faculty of Medicine, Alborz University of Medical Sciences, Karaj, Iran., Hashemnejad MA; Cellular and Molecular Research Center, Iran University of Medical Sciences, Tehran, Iran., Bastan Sarabi N; Cellular and Molecular Research Center, Iran University of Medical Sciences, Tehran, Iran., Qorbani M; Non-communicable Diseases Research Center, Alborz University of Medical Sciences, Karaj, Iran., Dehghani M; Department of Oral and Maxillofacial, Faculty of Dentistry, Tehran Medical Sciences of Islamic Azad, University, Tehran, Iran., Ashrafi M; Department of Pediatric Neurology, Children's Medical Center, Tehran University of Medical Sciences, Tehran, Iran., Mostafavi K; Student Research Committee, Faculty of Medicine, Iran University of Medical Sciences, Tehran, Iran., Ketabforoush AHME; Cellular and Molecular Research Center, Iran University of Medical Sciences, Tehran, Iran., Nikkhah A; Pediatric Neurology Department, Mofid Children's Hospital, Faculty of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Jazyk:	angličtina
Zdroj:	Iranian journal of child neurology [Iran J Child Neurol] 2023 Summer; Vol. 17 (3), pp. 69-80. Date of Electronic Publication: 2023 Jul 01.
DOI:	10.22037/ijcn.v17i2.36829
Abstrakt:	Objectives: The SARS-CoV-2 pandemic is the most challenging crisis in the contemporary world. Besides severe pulmonary involvement, the disease also has several extrapulmonary manifestations, and new signs and symptoms are associated with it every dayThe present study aimed to inquire about the frequency of neurological manifestations and risk factors of COVID-19. Materials & Methods: This retrospective, descriptive study included patients with neurological involvement admitted to the Alborz University of Medical Sciences academic hospitals from March 2020 to July 2020 with confirmed COVID-19 infection. The data included in the analysis were the patient's demographic information, underlying diseases, neurological manifestations, and laboratory findings. Results: The study included ninety-five patients with a mean age of fifty-nine. Neurological symptoms and signs were observed in 91.6% and 10.5% of the patients, respectively. The most frequently associated neurological symptoms of COVID-19 were fatigue (49.5%), headache (47.4%), and dizziness (45.3%). Furthermore, the most common neurological involvements included gait disorders (6.3%), cerebellar dysfunction (4.2%), and cerebrovascular accidents (3.15%). Positive troponin was shown to be the strongest predictor of neurological signs (OR=21, P=0.017), followed by WBC≥15,000 (OR = 20.75, P=0.018) and a history of respiratory disease (OR=7.42, P=0.007). Conclusion: Neurological symptoms were observed in more than 91% of the patients, while neurological signs were present in 10.5% of the COVID-19 patients. Additionally, positive troponin, WBC≥15,000, and a history of respiratory disease were the strongest predictors of neurological signs. Competing Interests: The authors have no conflicts of interest to declare regarding the content of this article.
Databáze:	MEDLINE
Externí odkaz:	Zobrazit plný text záznamu