Pattern of metastasis of head and neck cancer in Nigeria: A 10 year review.
| Autor: | Okwor VC; Department of Radiation and Clinical Oncology, University of Nigeria Teaching Hospital Ituku/Ozalla, Enugu, Nigeria., Folasire A; Department of Radiotherapy, University of Ibadan, Oyo State, Nigeria., Ntekim AI; Department of Radiotherapy, University of Ibadan, Oyo State, Nigeria., Okwor CJ; Department of Chemical Pathology, College of Medicine, University of Nigeria Ituku/Ozalla Campus, Enugu, Nigeria., Nwankwo KC; Department of Radiation Medicine, University of Nigeria, Enugu Campus, Enugu, Nigeria., Arua SC; Department of Radiation Medicine, University of Abuja Teaching Hospital, Gwagwalada Abuja, Nigeria. |
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| Jazyk: | angličtina |
| Zdroj: | Nigerian journal of clinical practice [Niger J Clin Pract] 2023 Jul; Vol. 26 (7), pp. 847-855. |
| DOI: | 10.4103/njcp.njcp_1385_21 |
| Abstrakt: | Introduction: Head and neck cancer is a common and aggressive malignancy with a high morbidity and mortality profile that occur in several anatomical sites in the head and neck region. They constitute the tenth most common cancer in the world. Metastatic head and neck cancers are associated with severe morbidities and its treatment is mainly palliative. This study examined the patterns of metastases of head and neck cancer in patients in a tertiary hospital in Nigeria. Method: The data extraction form was used to obtain information from the Radiotherapy treatments records and the case notes of patients with histological diagnosis of Head and Neck Cancers between 2002 and 2011 at the Radiotherapy department, University College Hospital, Ibadan. Analyses was done using statistical Package for Social Sciences (SPSS) Version 20.0. Results: A total of 481 patients were seen in this study. The age of the patients ranged from 11 years to 80 years with mean age of 42 years. The male to female ratio was 2:1. The peak age of incidence was between 40-49 years. Most patients presented with stage III and IV. Nasopharyngeal carcinoma had the highest proportion of occurrence 205 (42.6%) followed by paranasal sinuses. Lung had the commonest site of metastasis followed by bones. Conclusion: More than half of the patients presented late with the commonest cancer being nasopharyngeal carcinoma. Lung was the commonest site of distant metastasis with nasopharyngeal carcinoma having the highest proportion of metastasis to the lungs at two years follow up. Competing Interests: None |
| Databáze: | MEDLINE |
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