Antibacterial Cu or Zn-MOFs Based on the 1,3,5-Tris-(styryl)benzene Tricarboxylate.

Autor: Lelouche SNK; Advanced Porous Materials Unit, IMDEA Energy Institute, Av. Ramón de la Sagra 3, Mostoles, 28935 Madrid, Spain.; Escuela Internacional de Doctorado, Universidad Rey Juan Carlos, c/ Tulipan, s/n, Mostoles, 28933 Madrid, Spain., Albentosa-González L; Centro Regional de Investigaciones Biomédicas (CRIB), Universidad de Castilla-La Mancha, C/Almansa 14, 02008 Albacete, Spain.; Facultad de Farmacia, Universidad de Castilla-La Mancha, Av. Dr. José María Sánchez Ibáñez, s/n, 02008 Albacete, Spain., Clemente-Casares P; Centro Regional de Investigaciones Biomédicas (CRIB), Universidad de Castilla-La Mancha, C/Almansa 14, 02008 Albacete, Spain.; Facultad de Farmacia, Universidad de Castilla-La Mancha, Av. Dr. José María Sánchez Ibáñez, s/n, 02008 Albacete, Spain., Biglione C; Advanced Porous Materials Unit, IMDEA Energy Institute, Av. Ramón de la Sagra 3, Mostoles, 28935 Madrid, Spain., Rodríguez-Diéguez A; Departamento de Química Inorgánica, Universidad de Granada, Av. Fuentenueva s/n, 18071 Granada, Spain., Tolosa Barrilero J; Centro Regional de Investigaciones Biomédicas (CRIB), Universidad de Castilla-La Mancha, C/Almansa 14, 02008 Albacete, Spain.; Facultad de Farmacia, Universidad de Castilla-La Mancha, Av. Dr. José María Sánchez Ibáñez, s/n, 02008 Albacete, Spain., García-Martínez JC; Centro Regional de Investigaciones Biomédicas (CRIB), Universidad de Castilla-La Mancha, C/Almansa 14, 02008 Albacete, Spain.; Facultad de Farmacia, Universidad de Castilla-La Mancha, Av. Dr. José María Sánchez Ibáñez, s/n, 02008 Albacete, Spain., Horcajada P; Advanced Porous Materials Unit, IMDEA Energy Institute, Av. Ramón de la Sagra 3, Mostoles, 28935 Madrid, Spain.
Jazyk: angličtina
Zdroj: Nanomaterials (Basel, Switzerland) [Nanomaterials (Basel)] 2023 Aug 09; Vol. 13 (16). Date of Electronic Publication: 2023 Aug 09.
DOI: 10.3390/nano13162294
Abstrakt: Metal-organic frameworks (MOFs) are highly versatile materials. Here, two novel MOFs, branded as IEF-23 and IEF-24 and based on an antibacterial tricarboxylate linker and zinc or copper cations, and holding antibacterial properties, are presented. The materials were synthesized by the solvothermal route and fully characterized. The antibacterial activity of IEF-23 and IEF-24 was investigated against Staphylococcus epidermidis and Escherichia coli via the agar diffusion method. These bacteria are some of the most broadly propagated pathogens and are more prone to the development of antibacterial resistance. As such, they represent an archetype to evaluate the efficiency of novel antibacterial treatments. MOFs were active against both strains, exhibiting higher activity against Staphylococcus epidermidis . Thus, the potential of the developed MOFs as antibacterial agents was proved.
Databáze: MEDLINE
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