Gender differences in the associations between childhood adversity and psychopathology in the general population.

Autor: Prachason T; Department of Psychiatry, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok, Thailand.; Department of Psychiatry and Neuropsychology, School for Mental Health and Neuroscience, Maastricht University Medical Center, P.O. Box 616, 6200 MD, Maastricht, The Netherlands., Mutlu I; Institute of Graduate Programs, Department of Clinical Psychology, Istanbul Bilgi University, Istanbul, Turkey., Fusar-Poli L; Department of Brain and Behavioral Sciences, University of Pavia, Pavia, Italy., Menne-Lothmann C; Department of Psychiatry and Neuropsychology, School for Mental Health and Neuroscience, Maastricht University Medical Center, P.O. Box 616, 6200 MD, Maastricht, The Netherlands., Decoster J; Psychiatric Care Sint-Kamillus, Bierbeek, Belgium., van Winkel R; Department of Psychiatry and Neuropsychology, School for Mental Health and Neuroscience, Maastricht University Medical Center, P.O. Box 616, 6200 MD, Maastricht, The Netherlands.; Department of Neurosciences, University Psychiatric Centre KU Leuven, KU Leuven, Leuven, Belgium., Collip D; Department of Psychiatry and Neuropsychology, School for Mental Health and Neuroscience, Maastricht University Medical Center, P.O. Box 616, 6200 MD, Maastricht, The Netherlands., Delespaul P; Department of Psychiatry and Neuropsychology, School for Mental Health and Neuroscience, Maastricht University Medical Center, P.O. Box 616, 6200 MD, Maastricht, The Netherlands., De Hert M; University Psychiatric Centre Katholieke Universiteit Leuven, Kortenberg, Belgium.; Department of Neurosciences, Centre for Clinical Psychiatry, Katholieke Universiteit Leuven, Leuven, Belgium.; Leuven Brain Institute, Katholieke Universiteit Leuven, Leuven, Belgium.; Antwerp Health Law and Ethics Chair, University of Antwerp, Antwerp, Belgium., Derom C; Department of Obstetrics and Gynecology, Ghent University Hospitals, Ghent University, Ghent, Belgium., Thiery E; Department of Neurology, Ghent University Hospital, Ghent University, Ghent, Belgium., Jacobs N; Department of Psychiatry and Neuropsychology, School for Mental Health and Neuroscience, Maastricht University Medical Center, P.O. Box 616, 6200 MD, Maastricht, The Netherlands.; Faculty of Psychology, Open University of the Netherlands, Heerlen, The Netherlands., Wichers M; Department of Psychiatry and Neuropsychology, School for Mental Health and Neuroscience, Maastricht University Medical Center, P.O. Box 616, 6200 MD, Maastricht, The Netherlands.; Department of Psychiatry, Interdisciplinary Center Psychopathology and Emotion Regulation (ICPE), University of Groningen, University Medical Center Groningen, Groningen, The Netherlands., van Os J; Department of Psychiatry and Neuropsychology, School for Mental Health and Neuroscience, Maastricht University Medical Center, P.O. Box 616, 6200 MD, Maastricht, The Netherlands.; Department of Psychiatry, Brain Centre Rudolf Magnus, University Medical Centre Utrecht, Utrecht, The Netherlands.; Department of Psychosis Studies, Institute of Psychiatry, King's Health Partners, King's College London, London, UK., Rutten BPF; Department of Psychiatry and Neuropsychology, School for Mental Health and Neuroscience, Maastricht University Medical Center, P.O. Box 616, 6200 MD, Maastricht, The Netherlands., Pries LK; Department of Psychiatry and Neuropsychology, School for Mental Health and Neuroscience, Maastricht University Medical Center, P.O. Box 616, 6200 MD, Maastricht, The Netherlands., Guloksuz S; Department of Psychiatry and Neuropsychology, School for Mental Health and Neuroscience, Maastricht University Medical Center, P.O. Box 616, 6200 MD, Maastricht, The Netherlands. sinan.guloksuz@maastrichtuniversity.nl.; Department of Psychiatry, Yale School of Medicine, New Haven, CT, USA. sinan.guloksuz@maastrichtuniversity.nl.
Jazyk: angličtina
Zdroj: Social psychiatry and psychiatric epidemiology [Soc Psychiatry Psychiatr Epidemiol] 2024 May; Vol. 59 (5), pp. 847-858. Date of Electronic Publication: 2023 Aug 25.
DOI: 10.1007/s00127-023-02546-5
Abstrakt: Purpose: To explore gender differences of the associations between childhood adversity (CA) subtypes and psychiatric symptoms in the general population.
Methods: Data of 791 participants were retrieved from a general population twin cohort. The Symptom Checklist-90 Revised (SCL-90) and the Childhood Trauma Questionnaire were used to assess overall psychopathology with nine symptom domains scores and total CA with exposure to five CA subtypes, respectively. The associations between CA and psychopathology were analyzed in men and women separately and were subsequently compared.
Results: Total CA was associated with total SCL-90 and all symptom domains without significant gender differences. However, the analyses of CA subtypes showed that the association between emotional abuse and total SCL-90 was stronger in women compared to men [χ 2 (1) = 4.10, P = 0.043]. Sexual abuse was significantly associated with total SCL-90 in women, but emotional neglect and physical neglect were associated with total SCL-90 in men. Exploratory analyses of CA subtypes and SCL-90 subdomains confirmed the pattern of gender-specific associations. In women, emotional abuse was associated with all symptom domains, and sexual abuse was associated with all except phobic anxiety and interpersonal sensitivity. In men, emotional neglect was associated with depression, and physical neglect was associated with phobic anxiety, anxiety, interpersonal sensitivity, obsessive-compulsive, paranoid ideation, and hostility subdomains.
Conclusion: CA is a trans-syndromal risk factor regardless of gender. However, differential associations between CA subtypes and symptom manifestation might exist. Abuse might be particularly associated with psychopathology in women, whereas neglect might be associated with psychopathology in men.
(© 2023. The Author(s).)
Databáze: MEDLINE
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