Assessment of Hypertensive Patients' Complex Metabolic Status Using Data Mining Methods.

Autor:	Kovács B; Division of Metabolic Diseases, Department of Internal Medicine, Faculty of Medicine, University of Debrecen, H-4032 Debrecen, Hungary., Németh Á; Division of Metabolic Diseases, Department of Internal Medicine, Faculty of Medicine, University of Debrecen, H-4032 Debrecen, Hungary., Daróczy B; Institute for Computer Science and Control (SZTAKI), Hungarian Research Network, H-1111 Budapest, Hungary.; Department of Mathematical Engineering (INMA/ICTEAM), Université Catholique de Louvain, 1348 Louvain-la-Neuve, Belgium., Karányi Z; Division of Metabolic Diseases, Department of Internal Medicine, Faculty of Medicine, University of Debrecen, H-4032 Debrecen, Hungary., Maroda L; Department of Medical Clinical Pharmacology, Faculty of Medicine, University of Debrecen, H-4032 Debrecen, Hungary., Diószegi Á; Division of Metabolic Diseases, Department of Internal Medicine, Faculty of Medicine, University of Debrecen, H-4032 Debrecen, Hungary., Harangi M; Division of Metabolic Diseases, Department of Internal Medicine, Faculty of Medicine, University of Debrecen, H-4032 Debrecen, Hungary.; Institute of Health Studies, Faculty of Health Sciences, University of Debrecen, H-4032 Debrecen, Hungary., Páll D; Department of Medical Clinical Pharmacology, Faculty of Medicine, University of Debrecen, H-4032 Debrecen, Hungary.
Jazyk:	angličtina
Zdroj:	Journal of cardiovascular development and disease [J Cardiovasc Dev Dis] 2023 Aug 13; Vol. 10 (8). Date of Electronic Publication: 2023 Aug 13.
DOI:	10.3390/jcdd10080345
Abstrakt:	Cardiovascular diseases are among the leading causes of mortality worldwide. Hypertension is a preventable risk factor leading to major cardiovascular events. We have not found a comprehensive study investigating Central and Eastern European hypertensive patients' complex metabolic status. Therefore, our goal was to calculate the prevalence of hypertension and associated metabolic abnormalities using data-mining methods in our region. We assessed the data of adults who visited the University of Debrecen Clinical Center's hospital (n = 937,249). The study encompassed data from a period of 20 years (2001-2021). We detected 292,561 hypertensive patients. The calculated prevalence of hypertension was altogether 32.2%. Markedly higher body mass index values were found in hypertensive patients as compared to non-hypertensives. Significantly higher triglyceride and lower HDL-C levels were found in adults from 18 to 80 years old. Furthermore, significantly higher serum glucose and uric acid levels were measured in hypertensive subjects. Our study confirms that the calculated prevalence of hypertension is akin to international findings and highlights the extensive association of metabolic alterations. These findings emphasize the role of early recognition and immediate treatment of cardiometabolic abnormalities to improve the quality of life and life expectancy of hypertensive patients.
Databáze:	MEDLINE
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