3D mouse pose from single-view video and a new dataset.

Autor: Hu B; Google, 1600 Amphitheatre Parkway, Mountain View, CA, 94043, USA. bhuroc@google.com., Seybold B; Google, 1600 Amphitheatre Parkway, Mountain View, CA, 94043, USA., Yang S; Google, 1600 Amphitheatre Parkway, Mountain View, CA, 94043, USA., Sud A; Google, 1600 Amphitheatre Parkway, Mountain View, CA, 94043, USA., Liu Y; Calico Life Sciences LLC, 1170 Veterans Blvd., South San Francisco, CA, 94080, USA., Barron K; Calico Life Sciences LLC, 1170 Veterans Blvd., South San Francisco, CA, 94080, USA., Cha P; Calico Life Sciences LLC, 1170 Veterans Blvd., South San Francisco, CA, 94080, USA., Cosino M; Calico Life Sciences LLC, 1170 Veterans Blvd., South San Francisco, CA, 94080, USA., Karlsson E; Calico Life Sciences LLC, 1170 Veterans Blvd., South San Francisco, CA, 94080, USA., Kite J; Calico Life Sciences LLC, 1170 Veterans Blvd., South San Francisco, CA, 94080, USA., Kolumam G; Calico Life Sciences LLC, 1170 Veterans Blvd., South San Francisco, CA, 94080, USA., Preciado J; Calico Life Sciences LLC, 1170 Veterans Blvd., South San Francisco, CA, 94080, USA., Zavala-Solorio J; Calico Life Sciences LLC, 1170 Veterans Blvd., South San Francisco, CA, 94080, USA., Zhang C; Calico Life Sciences LLC, 1170 Veterans Blvd., South San Francisco, CA, 94080, USA., Zhang X; Translational Imaging, Neuroscience Discovery, Abbvie, 1 N. Waukegan Rd., North Chicago, IL, 60064-1802, USA., Voorbach M; Translational Imaging, Neuroscience Discovery, Abbvie, 1 N. Waukegan Rd., North Chicago, IL, 60064-1802, USA., Tovcimak AE; Translational Imaging, Neuroscience Discovery, Abbvie, 1 N. Waukegan Rd., North Chicago, IL, 60064-1802, USA., Ruby JG; Calico Life Sciences LLC, 1170 Veterans Blvd., South San Francisco, CA, 94080, USA., Ross DA; Google, 1600 Amphitheatre Parkway, Mountain View, CA, 94043, USA.
Jazyk: angličtina
Zdroj: Scientific reports [Sci Rep] 2023 Aug 21; Vol. 13 (1), pp. 13554. Date of Electronic Publication: 2023 Aug 21.
DOI: 10.1038/s41598-023-40738-w
Abstrakt: We present a method to infer the 3D pose of mice, including the limbs and feet, from monocular videos. Many human clinical conditions and their corresponding animal models result in abnormal motion, and accurately measuring 3D motion at scale offers insights into health. The 3D poses improve classification of health-related attributes over 2D representations. The inferred poses are accurate enough to estimate stride length even when the feet are mostly occluded. This method could be applied as part of a continuous monitoring system to non-invasively measure animal health, as demonstrated by its use in successfully classifying animals based on age and genotype. We introduce the Mouse Pose Analysis Dataset, the first large scale video dataset of lab mice in their home cage with ground truth keypoint and behavior labels. The dataset also contains high resolution mouse CT scans, which we use to build the shape models for 3D pose reconstruction.
(© 2023. Springer Nature Limited.)
Databáze: MEDLINE
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