Glyphosate is Harmful to Early Life Stages of the Viviparous Fish Jenynsia Multidentata: Biochemical and Locomotor Effects.

Autor: Moraes JS; Programa de Pós-Graduação em Ciências Fisiológicas, Universidade Federal do Rio Grande, Instituto de Ciências Biológicas, Av. Itália Km 8, Rio Grande, RS, 96203-900, Brazil. jenifersilveiramoraes@hotmail.com., da Costa Silva DG; Programa de Pós-Graduação em Ciências Fisiológicas, Universidade Federal do Rio Grande, Instituto de Ciências Biológicas, Av. Itália Km 8, Rio Grande, RS, 96203-900, Brazil., Dos Santos Vaz B; Instituto Federal Sul-Rio-Grandense, Campus Pelotas. Praça Vinte de Setembro, Centro Pelotas, RS, 96015360, Brazil., Mizuschima CW; Instituto Federal Sul-Rio-Grandense, Campus Pelotas. Praça Vinte de Setembro, Centro Pelotas, RS, 96015360, Brazil., de Martinez Gaspar Martins C; Programa de Pós-Graduação em Ciências Fisiológicas, Universidade Federal do Rio Grande, Instituto de Ciências Biológicas, Av. Itália Km 8, Rio Grande, RS, 96203-900, Brazil.
Jazyk: angličtina
Zdroj: Archives of environmental contamination and toxicology [Arch Environ Contam Toxicol] 2023 Nov; Vol. 85 (4), pp. 417-428. Date of Electronic Publication: 2023 Aug 21.
DOI: 10.1007/s00244-023-01015-z
Abstrakt: Glyphosate is the most widely used herbicide worldwide due to its efficacy in weed control in agriculture. This herbicide has been consistently detected in the aquatic environment, causing harmful consequences to nontarget organisms residing in agricultural regions. In this study, we assessed the effects of environmentally relevant concentrations of glyphosate (30-100 µg/L) on the early life stages of the viviparous fish Jenynsia multidentata through biochemical and locomotor endpoints. At 96 h of exposure, 30 and 65 µg/L glyphosate caused an increase in acetylcholinesterase (AChE) activity, and 65 µg/L glyphosate also augmented the levels of lipid peroxidation. Glyphosate at 100 µg/L did not alter the activity of acetylcholinesterase or the levels of lipid peroxidation, but it stimulated the activity of the cellular detoxification enzyme glutathione S-transferase. In addition, all concentrations affected the swimming of the fish. Under light conditions, glyphosate caused hypolocomotion at all concentrations tested, whereas under dark conditions, this was observed at 30 and 100 µg/L. Hyperlocomotion was observed at 65 µg/L glyphosate. These findings are alarming for the health of fish, such as J. multidentata that inhabit streams that pass through agricultural areas, especially for the early life stages of these fish. Research studying the effects of pollutants on native species is relevant to improve regulation that protects aquatic ecosystems.
(© 2023. The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature.)
Databáze: MEDLINE
Externí odkaz: