Diverse presentations of ectopia lentis and lens coloboma in Marfan's syndrome.
| Autor: | Dhiman R; Department of Ophthalmology, Government Medical College, Chandigarh, India., Kaur L; Department of Ophthalmology, Maharishi Markandeshwar Institute of Medical Sciences and Research, Ambala, Haryana, India., Sharma N; Department of Ophthalmology, Maharishi Markandeshwar Institute of Medical Sciences and Research, Ambala, Haryana, India., Pandey ML; Department of Ophthalmology, Maharishi Markandeshwar Institute of Medical Sciences and Research, Ambala, Haryana, India. |
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| Jazyk: | angličtina |
| Zdroj: | Oman journal of ophthalmology [Oman J Ophthalmol] 2023 Jun 27; Vol. 16 (2), pp. 310-313. Date of Electronic Publication: 2023 Jun 27 (Print Publication: 2023). |
| DOI: | 10.4103/ojo.ojo_108_22 |
| Abstrakt: | Marfan's syndrome (MFS) is an autosomal dominant connective tissue disorder with defect in the fibrillin-1 gene. The most common ocular manifestation is subluxated lens in the superotemporal direction, accounting for 50%-85% of total cases. The association of lens coloboma with MFS has been described in literature, but the coexistence of lens coloboma with ectopia lentis is a rare feature. Here, we describe three cases of MFS including a case of bilateral lens coloboma with ectopia lentis: case 1 - a 39-year-old male with inferotemporal lens subluxation in the right eye and superotemporal lens subluxation in the left eye with open-angle glaucoma and high myopia, case 2 - a 15-year-old child with bilateral superonasal lens subluxation with lens coloboma, and case 3 - a 56-year-old female with bilateral lens coloboma. Case 1 and case 2 had clear lenses with good refractive correction; hence, they were optically rehabilitated with contact lenses, whereas case 3 was advised for cataract surgery. It is important to distinguish the lens coloboma from a more common entity, ectopia lentis as former usually remains stable while the latter might need a surgical intervention. Competing Interests: There are no conflicts of interest. (Copyright: © 2023 Oman Ophthalmic Society.) |
| Databáze: | MEDLINE |
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