Consumption of cashew nut induced anxiolytic-like behavior in dyslipidemic rats consuming a high fat diet.

Autor: de Castro Querino Dias C; Department of Food Engineering, Technology Centre, Federal University of Paraiba, João Pessoa, Paraiba, Brazil., Madruga MS; Department of Food Engineering, Technology Centre, Federal University of Paraiba, João Pessoa, Paraiba, Brazil., Almeida GHO; Animal Science Departament, Federal University of Paraiba, Areia, Paraiba, Brazil., de Melo MFFT; Department of Nutrition, Center of Education and Health, Federal University of Campina Grande, Cuité, Paraíba, Brazil., Viera VB; Department of Nutrition, Center of Education and Health, Federal University of Campina Grande, Cuité, Paraíba, Brazil., de Menezes Santos Bertozzo CC; Department of Nutrition, Center of Education and Health, Federal University of Campina Grande, Cuité, Paraíba, Brazil., Dutra LMG; Department of Food Engineering, Technology Centre, Federal University of Paraiba, João Pessoa, Paraiba, Brazil. Electronic address: lara-dutra@hotmail.com., Alves APV; Department of Nutrition, Center of Education and Health, Federal University of Campina Grande, Cuité, Paraíba, Brazil., Dantas FA; Department of Nutrition, Center of Education and Health, Federal University of Campina Grande, Cuité, Paraíba, Brazil., Bezerra JKG; Department of Nutrition, Center of Education and Health, Federal University of Campina Grande, Cuité, Paraíba, Brazil., Soares JKB; Department of Food Engineering, Technology Centre, Federal University of Paraiba, João Pessoa, Paraiba, Brazil; Department of Nutrition, Center of Education and Health, Federal University of Campina Grande, Cuité, Paraíba, Brazil.
Jazyk: angličtina
Zdroj: Behavioural brain research [Behav Brain Res] 2023 Sep 13; Vol. 453, pp. 114634. Date of Electronic Publication: 2023 Aug 18.
DOI: 10.1016/j.bbr.2023.114634
Abstrakt: This study aimed to evaluate the effect of cashew nut consumption on anxiety-like behavior in dyslipidemic rats. The groups formed were: Control (CONT), Dyslipidemic (DL) and Dyslipidemic cashew nuts (DLCN). Tests to assess anxiety parameters were performed after the treatment period. Brain fatty acid profiles were analyzed. The animals in the DLCN group showed more rearing than DL, without differing from the CONT and less grooming than either the DL and CONT in the Open Field. In the Elevated Plus Maze, DLCN spent more time on the open arms and in the central area compared to the other groups. As for brain fatty acids, there was a reduction in polyunsaturated fatty acids for the DLCN compared to the other groups. The cashew nut, rich in fatty acids, phenolic and flavonoid compounds, reduced the anxiogenic-like behavior caused by dyslipidemia in rats without altering brain fatty acids.
(Copyright © 2023. Published by Elsevier B.V.)
Databáze: MEDLINE
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