Attaching protein-adsorbing silica particles to the surface of cotton substrates for bioaerosol capture including SARS-CoV-2.

Autor: Collings K; Department of Electrical Engineering and Electronics, University of Liverpool, Liverpool, UK., Boisdon C; Department of Electrical Engineering and Electronics, University of Liverpool, Liverpool, UK., Sham TT; Department of Electrical Engineering and Electronics, University of Liverpool, Liverpool, UK., Skinley K; Department of Chemistry, University of Liverpool, Liverpool, UK., Oh HK; Department of Electrical Engineering and Electronics, University of Liverpool, Liverpool, UK., Prince T; Institute of Infection, Veterinary and Ecological Sciences, University of Liverpool, Liverpool, UK., Ahmed A; Department of Chemistry, University of Liverpool, Liverpool, UK., Pennington SH; Centre for Drugs and Diagnostics, Department of Tropical Disease Biology, Liverpool School of Tropical Medicine, Liverpool, UK., Brownridge PJ; Centre for Proteome Research, Department of Biochemistry & Systems Biology, Institute of Systems, Molecular & Integrative Biology, University of Liverpool, Liverpool, UK., Edwards T; Centre for Drugs and Diagnostics, Department of Tropical Disease Biology, Liverpool School of Tropical Medicine, Liverpool, UK., Biagini GA; Centre for Drugs and Diagnostics, Department of Tropical Disease Biology, Liverpool School of Tropical Medicine, Liverpool, UK., Eyers CE; Centre for Proteome Research, Department of Biochemistry & Systems Biology, Institute of Systems, Molecular & Integrative Biology, University of Liverpool, Liverpool, UK., Lamb A; Faculty of Health and Life Sciences, University of Liverpool, Liverpool, UK.; Applied Health Insights Ltd, Cheshire, UK., Myers P; Department of Chemistry, University of Liverpool, Liverpool, UK. peterm@liverpool.ac.uk., Maher S; Department of Electrical Engineering and Electronics, University of Liverpool, Liverpool, UK. s.maher@liverpool.ac.uk.
Jazyk: angličtina
Zdroj: Nature communications [Nat Commun] 2023 Aug 18; Vol. 14 (1), pp. 5033. Date of Electronic Publication: 2023 Aug 18.
DOI: 10.1038/s41467-023-40696-x
Abstrakt: The novel coronavirus pandemic (COVID-19) has necessitated a global increase in the use of face masks to limit the airborne spread of the virus. The global demand for personal protective equipment has at times led to shortages of face masks for the public, therefore makeshift masks have become commonplace. The severe acute respiratory syndrome caused by coronavirus-2 (SARS-CoV-2) has a spherical particle size of ~97 nm. However, the airborne transmission of this virus requires the expulsion of droplets, typically ~0.6-500 µm in diameter (by coughing, sneezing, breathing, and talking). In this paper, we propose a face covering that has been designed to effectively capture SARS-CoV-2 whilst providing uncompromised comfort and breathability for the wearer. Herein, we describe a material approach that uses amorphous silica microspheres attached to cotton fibres to capture bioaerosols, including SARS CoV-2. This has been demonstrated for the capture of aerosolised proteins (cytochrome c, myoglobin, ubiquitin, bovine serum albumin) and aerosolised inactivated SARS CoV-2, showing average filtration efficiencies of ~93% with minimal impact on breathability.
(© 2023. Springer Nature Limited.)
Databáze: MEDLINE
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