Investigating adverse effects of chronic dietary exposure to herbicide glyphosate on zootechnical characteristics and clinical, biochemical and immunological blood parameters in broiler chickens.

Autor: Yildirim EA; BIOTROF+ Ltd, Pushkin, St. Petersburg, Russia.; Federal State Budgetary Educational Institution of Higher Education 'St. Petersburg State Agrarian University', Pushkin, St. Petersburg, Russia., Laptev GY; BIOTROF+ Ltd, Pushkin, St. Petersburg, Russia.; Federal State Budgetary Educational Institution of Higher Education 'St. Petersburg State Agrarian University', Pushkin, St. Petersburg, Russia., Tiurina DG; BIOTROF+ Ltd, Pushkin, St. Petersburg, Russia., Gorfunkel EP; BIOTROF+ Ltd, Pushkin, St. Petersburg, Russia., Ilina LA; BIOTROF+ Ltd, Pushkin, St. Petersburg, Russia.; Federal State Budgetary Educational Institution of Higher Education 'St. Petersburg State Agrarian University', Pushkin, St. Petersburg, Russia., Filippova VA; BIOTROF+ Ltd, Pushkin, St. Petersburg, Russia.; Federal State Budgetary Educational Institution of Higher Education 'St. Petersburg State Agrarian University', Pushkin, St. Petersburg, Russia., Dubrovin AV; BIOTROF+ Ltd, Pushkin, St. Petersburg, Russia., Brazhnik EA; BIOTROF+ Ltd, Pushkin, St. Petersburg, Russia., Novikova NI; BIOTROF+ Ltd, Pushkin, St. Petersburg, Russia., Melikidi VK; BIOTROF+ Ltd, Pushkin, St. Petersburg, Russia., Kalitkina KA; BIOTROF+ Ltd, Pushkin, St. Petersburg, Russia.; Federal State Budgetary Educational Institution of Higher Education 'St. Petersburg State Agrarian University', Pushkin, St. Petersburg, Russia., Ponomareva ES; BIOTROF+ Ltd, Pushkin, St. Petersburg, Russia., Griffin DK; School of Biosciences, University of Kent, Canterbury, UK., Romanov MN; School of Biosciences, University of Kent, Canterbury, UK. m.romanov@kent.ac.uk.; L. K. Ernst Federal Research Centre for Animal Husbandry, Dubrovitsy, Podolsk, Moscow Oblast, Russia. m.romanov@kent.ac.uk.
Jazyk: angličtina
Zdroj: Veterinary research communications [Vet Res Commun] 2024 Feb; Vol. 48 (1), pp. 153-164. Date of Electronic Publication: 2023 Aug 18.
DOI: 10.1007/s11259-023-10195-x
Abstrakt: Although the herbicide glyphosate is widely used globally and considered safe, more evidence of its adverse effects on animals and humans is accumulating. The present investigation was aimed at evaluating the impact of different glyphosate concentrations on zootechnical characteristics and clinical, biochemical and immunological blood parameters in Ross 308 broiler chickens. Four groups were employed, including untreated control and three experimental groups fed diets enriched with glyphosate at doses of 10, 20 and 100 ppm that conformed to 0.5, 1 and 5 maximum residue limits, respectively. The results showed that glyphosate is a stress factor triggering a multifaceted effect on important blood parameters (e.g., white blood cell and phagocytic counts), which was shown for the first time in the experiments involving productive meat-type poultry. It was first revealed that glyphosate-induced changes in blood parameters may be related to a negative impact on the zootechnical characteristics including the digestive tract organ development and body weight gain. The study findings suggested that exposure to glyphosate in the feedstuffs can adversely affect the physiological condition and productivity of broilers.
(© 2023. The Author(s).)
Databáze: MEDLINE
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