[Skin aging exposome].
Autor: | Krutmann J; IUF - Leibniz-Institut für umweltmedizinische Forschung, Auf'm Hennekamp 50, 40225, Düsseldorf, Deutschland. jean.krutmann@iuf-duesseldorf.de., Grether-Beck S; IUF - Leibniz-Institut für umweltmedizinische Forschung, Auf'm Hennekamp 50, 40225, Düsseldorf, Deutschland., Makrantonaki E; Derma Zentrum Wildeshausen, Wildeshausen, Deutschland.; Klinik für Dermatologie und Allergologie, Universitätsmedizin Ulm, Ulm, Deutschland.; Medizinische Hochschule Brandenburg Theodor Fontane, Neuruppin, Deutschland., Schikowski T; IUF - Leibniz-Institut für umweltmedizinische Forschung, Auf'm Hennekamp 50, 40225, Düsseldorf, Deutschland. |
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Jazyk: | němčina |
Zdroj: | Dermatologie (Heidelberg, Germany) [Dermatologie (Heidelb)] 2023 Sep; Vol. 74 (9), pp. 657-662. Date of Electronic Publication: 2023 Aug 18. |
DOI: | 10.1007/s00105-023-05210-w |
Abstrakt: | The skin is a barrier organ and thus exposed to environmental factors from birth, which essentially determine skin aging. In order to describe and understand this complex process exactly, we applied the concept of the "exposome" to the environmentally induced skin aging process. In this review, we summarize current knowledge on the skin aging exposome. In this context, we characterize the most important exposomal factors, address their relative importance for skin aging and also the relevance of their mutual interactions. Finally, we discuss the clinical consequences resulting from this concept for an effective prevention of skin aging. (© 2023. The Author(s), under exclusive licence to Springer Medizin Verlag GmbH, ein Teil von Springer Nature.) |
Databáze: | MEDLINE |
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