Left Ventricular Outflow Occlusion: An Alternative Approach to Late Selective Fetal Termination in Monochorionic Twin Gestations.

Autor: Brown RN; Obstetrics and Gynecology, McGill University, Montreal, CAN., Morency AM; Obstetrics and Gynecology, McGill University, Montreal, CAN.
Jazyk: angličtina
Zdroj: Cureus [Cureus] 2023 Jul 16; Vol. 15 (7), pp. e41974. Date of Electronic Publication: 2023 Jul 16 (Print Publication: 2023).
DOI: 10.7759/cureus.41974
Abstrakt: We report the case of a monochorionic twin gestation discordant for a mutation in the chromodomain-helicase-DNA-binding protein 7 (CHD7) gene and cerebral abnormalities consequent to an early devastating cerebrovascular event. The parents elected for selective termination given the poor prognosis for this fetus, but given socio-economic considerations wished to defer this procedure as late in gestation as possible, despite awareness of the risks and limitations of existing techniques at the end of pregnancy.  A novel technique was used to achieve selective feticide in the late-preterm period. An endovascular balloon catheter was used to occlude the left ventricular outflow and coronary circulations resulting in fetal asystole while also arresting fetoplacental flow in this fetus, immediately prior to the delivery of the healthy fetus.
Competing Interests: The authors have declared that no competing interests exist.
(Copyright © 2023, Brown et al.)
Databáze: MEDLINE