The growth and developmental of the myodural bridge and its associated structures in the human fetus.

Autor: Song Y; Department of Anatomy, College of Basic Medicine, Dalian Medical University, Dalian, 116044, Liaoning, China., Lai HX; Department of Anatomy, College of Basic Medicine, Dalian Medical University, Dalian, 116044, Liaoning, China., Song TW; Department of Anatomy, College of Basic Medicine, Dalian Medical University, Dalian, 116044, Liaoning, China.; Department of Neurology, Angang Group Company General Hospital, Anshan, 114000, Liaoning, China., Gong J; Department of Anatomy, College of Basic Medicine, Dalian Medical University, Dalian, 116044, Liaoning, China., Liu B; Department of Histology and Embryology, College of Basic Medicine, Dalian Medical University, Dalian, 116044, Liaoning, China., Chi YY; Department of Anatomy, College of Basic Medicine, Dalian Medical University, Dalian, 116044, Liaoning, China., Yue C; Department of Anatomy, College of Basic Medicine, Dalian Medical University, Dalian, 116044, Liaoning, China.; Department of Obstetrics and Gynecology, Affiliated Zhongshan Hospital of Dalian University, Dalian, 116001, Liaoning, China., Zhang J; Department of Anatomy, College of Basic Medicine, Dalian Medical University, Dalian, 116044, Liaoning, China., Sun SZ; Basic and Clinical Medicine Teaching Laboratory, School of Medicine, Sun-Yat-Sen-University, Guangdong, 518100, China., Zhang CH; Morphology Laboratory, College of Basic Medicine, Dalian Medical University, Dalian, 116044, Liaoning, China., Tang W; Department of Anatomy, College of Basic Medicine, Dalian Medical University, Dalian, 116044, Liaoning, China., Fan N; Department of Anatomy, College of Basic Medicine, Dalian Medical University, Dalian, 116044, Liaoning, China., Yu WH; Department of Obstetrics and Gynecology, Lvshun District Hospital, Dalian, 116044, Liaoning, China., Wang YF; Department of Obstetrics and Gynecology, Affiliated Zhongshan Hospital of Dalian University, Dalian, 116001, Liaoning, China., Hack GD; Department of Advanced Oral Sciences and Therapeutics, University of Maryland School of Dentistry, Baltimore, MD, 21201, USA., Yu SB; Department of Anatomy, College of Basic Medicine, Dalian Medical University, Dalian, 116044, Liaoning, China., Zhang JF; Department of Anatomy, College of Basic Medicine, Dalian Medical University, Dalian, 116044, Liaoning, China. zjfdlmedu@163.com., Sui HJ; Department of Anatomy, College of Basic Medicine, Dalian Medical University, Dalian, 116044, Liaoning, China. suihj@hotmail.com.
Jazyk: angličtina
Zdroj: Scientific reports [Sci Rep] 2023 Aug 17; Vol. 13 (1), pp. 13421. Date of Electronic Publication: 2023 Aug 17.
DOI: 10.1038/s41598-023-40709-1
Abstrakt: Myodural bridge (MDB) is a dense connective tissue between suboccipital muscle and dura mater. However, there are few reports on the development and maturation of the human MDB. This study aims to explore the developmental relationship between suboccipital muscle and MDB. 30 head and neck specimens from human fetuses (F) ranging from the 12th to 41st week (W) were made into histological sections. The F12W sections showed evidence that the dura mater dominated by fibroblasts, attached to the posterior atlanto-axial membrane (PAAM) which completely sealed the atlanto-axial space. In the F13W stage, myofibrils of the suboccipital muscle fibers increased significantly in number. At the F14W stage, a gap was observed at the caudal end of the PAAM. Numerous myodural bridge-like structures were observed blending into the dura mater through the gap. At the F19W stage, muscle cells mature. Starting at the F21W stage, the MDB were observed as fibroblasts that cross the atlanto-axial interspace and attach to the dura mater. Therefore, the traction generated by the suboccipital muscles seems to promote the maturity of MDB. This study will provide new morphological knowledge to support future research on the function of the human MDB and regulating the development mechanism of MDB.
(© 2023. Springer Nature Limited.)
Databáze: MEDLINE
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