True mineral digestibility in C57Bl/6J mice.

Autor: Böswald LF; Chair for Animal Nutrition and Dietetics, Department of Veterinary Sciences, Faculty of Veterinary Medicine, LMU München, München, Germany., Wenderlein J; Chair of Bacteriology and Mycology, Institute of Infectious Diseases and Zoonoses, Department of Veterinary Sciences, Faculty of Veterinary Medicine, LMU München, München, Germany., Siegert W; Institute of Animal Science, University of Hohenheim, Stuttgart, Germany., Straubinger RK; Chair of Bacteriology and Mycology, Institute of Infectious Diseases and Zoonoses, Department of Veterinary Sciences, Faculty of Veterinary Medicine, LMU München, München, Germany., Kienzle E; Chair for Animal Nutrition and Dietetics, Department of Veterinary Sciences, Faculty of Veterinary Medicine, LMU München, München, Germany.
Jazyk: angličtina
Zdroj: PloS one [PLoS One] 2023 Aug 16; Vol. 18 (8), pp. e0290145. Date of Electronic Publication: 2023 Aug 16 (Print Publication: 2023).
DOI: 10.1371/journal.pone.0290145
Abstrakt: Data on mineral digestibility is key to understand mineral homeostasis and refine the recommendations for the dietary intake of these nutrients. In farm animals and pets, there is plenty of data on mineral digestibility and influencing factors. In laboratory mice, however, there is a lack of information on mineral digestibility under maintenance conditions, although this should be the basis for studies on mineral homeostasis under experimental conditions. The aim of the present study was to analyse data on intake, faecal excretion, and apparent digestibility of calcium, phosphorus, sodium, potassium, and magnesium in C57BL/6J mice fed different maintenance diets with varying voluntary dry matter intake. Lucas-tests were used to quantify true digestibility and describe correlations between dietary intake and excretion/absorption of the nutrients. Calcium, phosphorus, and magnesium showed a linear correlation between intake and faecal excretion (R2: 0.77, 0.93 and 0.91, respectively). Intake and apparently digested amounts of sodium and potassium were correlated linearly (R2: 0.86 and 0.98, respectively). These data show that intake is the major determinant of absorption in the minerals listed above. Faecal calcium and phosphorus excretion were correlated as well (R2 = 0.75).
Competing Interests: The authors have declared that no competing interests exist.
(Copyright: © 2023 Böswald et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.)
Databáze: MEDLINE
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