Case report: Atypical Parkinsonism following SARS-CoV-2 infection.
Autor: | Polverino P; Department of Neurology, IRCCS Humanitas Research Hospital, Milan, Italy., De Santis T; Department of Neurology, IRCCS Humanitas Research Hospital, Milan, Italy., Perdixi E; Department of Neurology, IRCCS Humanitas Research Hospital, Milan, Italy., Chiò A; ALS Centre 'Rita Levi Montalcini,' Department of Neuroscience, University of Turin, Turin, Italy.; Azienda Ospedaliero-Universitaria Città della Salute e della Scienza, Turin, Italy., Albanese A; Department of Neurology, IRCCS Humanitas Research Hospital, Milan, Italy.; Department of Neuroscience, Catholic University, Rome, Italy. |
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Jazyk: | angličtina |
Zdroj: | Frontiers in neurology [Front Neurol] 2023 Jul 31; Vol. 14, pp. 1208213. Date of Electronic Publication: 2023 Jul 31 (Print Publication: 2023). |
DOI: | 10.3389/fneur.2023.1208213 |
Abstrakt: | A wide range of neurological manifestations have been reported during the COVID-19 pandemic, including a variety of Parkinsonian cases. The association of numerous viruses with the development of persistent or transient Parkinsonism has been well-documented. We observed a patient who developed a levodopa non-responsive Parkinsonian syndrome with dysautonomia during a prolonged stay at home for COVID-19. Although the temporal proximity of the emerging Parkinsonian features with a COVID-19 diagnosis suggested a causal relationship, we considered the possibility of a coincidental occurrence of multiple system atrophy. We discuss the patient's clinical features in relation to the established clinical diagnostic criteria and review differential diagnoses as well as the role of SARS-CoV-2 infection. Competing Interests: The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest. (Copyright © 2023 Polverino, De Santis, Perdixi, Chiò and Albanese.) |
Databáze: | MEDLINE |
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