Increased Risk of Celiac Disease in Patients with Uveitis.
| Autor: | Milstein Y; Department of Ophthalmology, Hadassah-Hebrew University Medical Center, Jerusalem, Israel., Haiimov E; Department of Pediatric Gastroenterology, Hadassah Medical Center, Faculty of Medicine, Hebrew University of Jerusalem, Jerusalem, Israel., Slae M; Department of Pediatric Gastroenterology, Hadassah Medical Center, Faculty of Medicine, Hebrew University of Jerusalem, Jerusalem, Israel., Davidovics Z; Department of Pediatric Gastroenterology, Hadassah Medical Center, Faculty of Medicine, Hebrew University of Jerusalem, Jerusalem, Israel., Millman P; Department of Pediatric Gastroenterology, Hadassah Medical Center, Faculty of Medicine, Hebrew University of Jerusalem, Jerusalem, Israel., Birimberg-Schwartz L; Department of Pediatric Gastroenterology, Hadassah Medical Center, Faculty of Medicine, Hebrew University of Jerusalem, Jerusalem, Israel.; Hadassah Organoid Center, Hadassah Medical Organization, Jerusalem, Israel., Benson A; Department of Gastroenterology, Hadassah-Hebrew University Medical Center, Jerusalem, Israel., Wilschanski M; Department of Pediatric Gastroenterology, Hadassah Medical Center, Faculty of Medicine, Hebrew University of Jerusalem, Jerusalem, Israel., Amer R; Department of Ophthalmology, Hadassah-Hebrew University Medical Center, Jerusalem, Israel. |
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| Jazyk: | angličtina |
| Zdroj: | Ocular immunology and inflammation [Ocul Immunol Inflamm] 2024 Sep; Vol. 32 (7), pp. 1330-1334. Date of Electronic Publication: 2023 Aug 14. |
| DOI: | 10.1080/09273948.2023.2243497 |
| Abstrakt: | Purpose: To examine whether patients with non-infectious uveitis (NIU) are at increased risk for celiac disease (CeD). Methods: Celiac antibody testing was completed in 112 patients. The control group included patients who had undergone upper endoscopy for suspicion of CeD. Results: 2/112 (1.79%) of patients with NIU had positive anti-tTG serology and CeD was confirmed in both patients. When compared to the expected risk of CeD in the general Israeli population of 0.31%, this corresponded to an odds ratio of 5.77 (95% CI 1.4118 to 23.4737, P = 0.049). Three additional patients had positive serology for CeD but the diagnosis was not confirmed. Conclusions: An increased risk of CeD was detected in patients with NIU. We therefore recommend screening for CeD in NIU patients. Larger prospective studies are required to further validate these results. |
| Databáze: | MEDLINE |
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