West Nile virus: The current situation in Egypt.

Autor:	Hassanien RT; Department of Virology, Animal Health Research Institute, Agriculture Research Center, 12618, Giza, Egypt., Hussein HA; Department of Virology, Animal Health Research Institute, Agriculture Research Center, 12618, Giza, Egypt., Abdelmegeed HK; Department of Virology, Animal Health Research Institute, Agriculture Research Center, 12618, Giza, Egypt., Abdelwahed DA; Department of Virology, Animal Health Research Institute, Agriculture Research Center, 12618, Giza, Egypt., Khattab OM; Genome Unit, Animal Health Research Institute, Agriculture Research Center, 12618, Giza, Egypt., Ali MH; Department of Virology, Animal Health Research Institute, Agriculture Research Center, 12618, Giza, Egypt., Habashi AR; Department of Virology, Animal Health Research Institute, Agriculture Research Center, 12618, Giza, Egypt.; Virus Strain Bank, Animal Health Research Institute, Agriculture Research Center, 12618, Giza, Egypt., Ibraheem EM; Department of Pathology, Animal Health Research Institute, Agriculture Research Center, 12618, Giza, Egypt., Shahein MA; Department of Virology, Animal Health Research Institute, Agriculture Research Center, 12618, Giza, Egypt., Abohatab EM; Department of Virology, Animal Health Research Institute, Agriculture Research Center, 12618, Giza, Egypt.
Jazyk:	angličtina
Zdroj:	Veterinary world [Vet World] 2023 May; Vol. 16 (5), pp. 1154-1160. Date of Electronic Publication: 2023 May 30.
DOI:	10.14202/vetworld.2023.1154-1160
Abstrakt:	Background and Aim: Due to climatic changes, arthropod-borne viruses have become a global health concern. In Egypt, West Nile virus (WNV) was initially detected in humans in 1950 and then in 1951, 1954, 1968, and 1989. Although WNV infection has been recorded in numerous Middle Eastern countries, its prevalence among the equine population in Egypt is unknown. This study aimed to investigate the current situation of vector-borne WNV in Egypt, estimate its seroprevalence, and assess the associated risk factors. Materials and Methods: We screened 1100 sera samples and nasal swabs from the same equids, 156 mosquito pools, and 336 oropharyngeal and cloacal swabs from migratory birds for WNV. The sera were investigated for the presence of immunoglobulin G (IgG) and immunoglobulin M (IgM) against WNV-prE. Real-time reverse transcription-polymerase chain reaction was used to detect WNV RNA in the nasal swab samples, mosquito pools, and migratory birds' oropharyngeal and cloacal swabs. Results: The seroprevalence showed positive IgG in sera samples collected from different districts. The data showed that horses were 1.65-fold more susceptible than donkeys, with male being 1.45 times more susceptible than females. Moreover, the tested equids samples were divided into three groups based on their age: <5 years, 5-10 years, and >10 years. The 5-10-year group was 1.1 and 1.61 times more vulnerable to infection than the <5- and >10 year groups. All the sera samples were negative for IgM. The nasal swabs from equids, oropharyngeal and cloacal swabs from migratory birds, and mosquito samples tested negative for WNV by molecular detection. Conclusion: Based on the obtained data, we recommend that effective control programs should be implemented to enable epidemiological investigations and understand the current situation of WNV in Egypt. Competing Interests: The authors declare that they have no competing interests. (Copyright: © Hassanien, et al.)
Databáze:	MEDLINE
Externí odkaz:	Zobrazit plný text záznamu Plný text ve formátu PDF