Evaluation of the Antibacterial Activity of Gentamicin in Combination with Essential Oils Isolated from Different Cultivars and Morphological Parts of Lavender ( Lavandula angustifolia Mill.) against Selected Bacterial Strains.

Autor: Adaszyńska-Skwirzyńska M; Department of Monogastric Animal Sciences, Faculty of Biotechnology and Animal Husbandry, West Pomeranian University of Technology in Szczecin, Janickiego Str. 29, 71-270 Szczecin, Poland., Zych S; Laboratory of Chromatography and Mass Spectrometry, Faculty of Biotechnology and Animal Husbandry, West Pomeranian University of Technology in Szczecin, Janickiego Str. 29, 71-270 Szczecin, Poland., Bucław M; Department of Monogastric Animal Sciences, Faculty of Biotechnology and Animal Husbandry, West Pomeranian University of Technology in Szczecin, Janickiego Str. 29, 71-270 Szczecin, Poland., Majewska D; Department of Monogastric Animal Sciences, Faculty of Biotechnology and Animal Husbandry, West Pomeranian University of Technology in Szczecin, Janickiego Str. 29, 71-270 Szczecin, Poland., Dzięcioł M; Department of Chemical Organic Technology and Polymeric Materials, Faculty of Chemical Technology and Engineering, West Pomeranian University of Technology in Szczecin, Piastów Ave. 42, 71-065 Szczecin, Poland., Szczerbińska D; Department of Monogastric Animal Sciences, Faculty of Biotechnology and Animal Husbandry, West Pomeranian University of Technology in Szczecin, Janickiego Str. 29, 71-270 Szczecin, Poland.
Jazyk: angličtina
Zdroj: Molecules (Basel, Switzerland) [Molecules] 2023 Jul 31; Vol. 28 (15). Date of Electronic Publication: 2023 Jul 31.
DOI: 10.3390/molecules28155781
Abstrakt: The aim of the study was to investigate the antibacterial effects of essential oils isolated from different cultivars and morphological parts of lavender ( Lavandula angustifolia Mill.) in combination with the aminoglycoside antibiotic gentamicin. This in vitro study analyzed the effectiveness of the combinations of gentamicin and lavender essential oils against the following strains: Staphylococcus aureus ATCC 25923, Staphylococcus aureus MRSA and Pseudomonas aeruginosa ATCC 9027. The effect of the combination of lavender oils with gentamicin was tested using the checkerboard method. A synergistic effect against S. aureus strain ATCC 25923 was found when gentamicin was combined with lavender essential oils isolated from flowers and leafy stalks (flowers: 'Blue River' FICI-0.192; 'Ellagance Purple' FICI-0.288; leafy stalks: 'Blue River' FICI-0.192; 'Ellagance Purple' FICI-0.320). A synergistic effect was also observed for the combination of gentamicin with lavender essential oils from flowers against the resistant strain of S. aureus (MRSA) ('Blue River' FICI-0,191; 'Ellagance Purple' FICI-0.263), as well as for the essential oils from leafy stalks ('Blue River' FICI-0.076; 'Ellagance Purple' FICI-0.089). No interaction was observed for the combination of studied essential oils with gentamicin against P. aeruginosa strain ATCC 9027 (FICI = 1.083-1.300).
Databáze: MEDLINE
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